Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene.
about
hSiah2 is a new Vav binding protein which inhibits Vav-mediated signaling pathwaysSLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activityBiological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteinsFunctional association between SLAP-130 and SLP-76 in Jurkat T cellsIdentification of two tyrosine phosphoproteins, pp70 and pp68, which interact with phospholipase Cgamma, Grb2, and Vav after B cell antigen receptor activationSH3P7 is a cytoskeleton adapter protein and is coupled to signal transduction from lymphocyte antigen receptors.Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferationVav family proteins couple to diverse cell surface receptorsRegulatory and signaling properties of the Vav familyInteraction of Vav with ENX-1, a putative transcriptional regulator of homeobox gene expressionAnalysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptorsp95vav associates with the nuclear protein Ku-70Vav2 is required for cell spreadingVav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activationInterference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tailRasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responsesRho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and diseaseVav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyteAssociation of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathwayInteractions between the protein-tyrosine kinase ZAP-70, the proto-oncoprotein Vav, and tubulin in Jurkat T cellsT cell activation through the CD43 molecule leads to Vav tyrosine phosphorylation and mitogen-activated protein kinase pathway activationSignal transduction by CD28 costimulatory receptor on T cells. B7-1 and B7-2 regulation of tyrosine kinase adaptor moleculesSos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptorsTyrosine 474 of ZAP-70 is required for association with the Shc adaptor and for T-cell antigen receptor-dependent gene activationDifferential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphataseThe adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteriaA novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1ARegulation of B-1 cell activation and its autoantibody production by Lyn kinase-regulated signallingsGene expression profiling of the rat endometriosis modelTyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcriptionFyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cellsVav in natural killer cells is tyrosine phosphorylated upon cross-linking of Fc gamma RIIIA and is constitutively associated with a serine/threonine kinaseStructural determinants for the biological activity of Vav proteins.Vav1 is a component of transcriptionally active complexes.Identification of the Drosophila melanogaster homologue of the mammalian signal transducer protein, Vav.p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cellsExpression of a Chimeric Antigen Receptor in Multiple Leukocyte Lineages in Transgenic MiceA Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNKGuanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells.Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity.
P2860
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P2860
Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Defective signalling through t ...... acking the vav proto-oncogene.
@en
type
label
Defective signalling through t ...... acking the vav proto-oncogene.
@en
prefLabel
Defective signalling through t ...... acking the vav proto-oncogene.
@en
P2093
P356
P1433
P1476
Defective signalling through t ...... acking the vav proto-oncogene.
@en
P2093
P2888
P304
P356
10.1038/374470A0
P407
P577
1995-03-01T00:00:00Z
P6179
1044869818