Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae.
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Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosomeProteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.Prp8 protein: at the heart of the spliceosomePrp8p dissection reveals domain structure and protein interaction sites.Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiaeThe network of protein-protein interactions within the human U4/U6.U5 tri-snRNPEfficient termination of transcription by RNA polymerase I requires the 5' exonuclease Rat1 in yeastFunctional roles of DExD/H-box RNA helicases in Pre-mRNA splicingSki2-like RNA helicase structures: common themes and complex assembliesRNA helicases in splicingThe architecture of the spliceosomal U4/U6.U5 tri-snRNP.Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutantsStructure and function of an RNase H domain at the heart of the spliceosomeStructural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2Mechanism for Aar2p function as a U5 snRNP assembly factorStructural basis for dual roles of Aar2p in U5 snRNP assemblyStructural Basis of Brr2-Prp8 Interactions and Implications for U5 snRNP Biogenesis and the Spliceosome Active SiteCryo-EM structure of the spliceosome immediately after branchingHow Slu7 and Prp18 cooperate in the second step of yeast pre-mRNA splicing.Mutational analysis identifies two separable roles of the Saccharomyces cerevisiae splicing factor Prp18.Assembly of Snu114 into U5 snRNP requires Prp8 and a functional GTPase domain.Spatial organization of protein-RNA interactions in the branch site-3' splice site region during pre-mRNA splicing in yeast.Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activationprp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeastThe yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2pPrp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing.Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway.Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors.Characterization of U4 and U6 interactions with the 5' splice site using a S. cerevisiae in vitro trans-splicing systemDetection of novel members, structure-function analysis and evolutionary classification of the 2H phosphoesterase superfamilyMalleable ribonucleoprotein machine: protein intrinsic disorder in the Saccharomyces cerevisiae spliceosome.A bird's-eye view of post-translational modifications in the spliceosome and their roles in spliceosome dynamicsMutations in ASCC3L1 on 2q11.2 are associated with autosomal dominant retinitis pigmentosa in a Chinese family.A mutation in a splicing factor that causes retinitis pigmentosa has a transcriptome-wide effect on mRNA splicing.A spliceosomal intron in Giardia lamblia.Distinct domains of splicing factor Prp8 mediate different aspects of spliceosome activationThree gene-targeted mouse models of RNA splicing factor RP show late-onset RPE and retinal degeneration.The MEP-1 zinc-finger protein acts with MOG DEAH box proteins to control gene expression via the fem-3 3' untranslated region in Caenorhabditis elegansDefinition of a spliceosome interaction domain in yeast Prp2 ATPase.Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p.
P2860
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P2860
Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Functional contacts with a ran ...... s of Saccharomyces cerevisiae.
@en
type
label
Functional contacts with a ran ...... s of Saccharomyces cerevisiae.
@en
prefLabel
Functional contacts with a ran ...... s of Saccharomyces cerevisiae.
@en
P2860
P1433
P1476
Functional contacts with a ran ...... s of Saccharomyces cerevisiae.
@en
P2093
R W van Nues
P2860
P304
P407
P577
2001-04-01T00:00:00Z