Expression of Nav1.7 in DRG neurons extends from peripheral terminals in the skin to central preterminal branches and terminals in the dorsal horn.
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Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models.Mechanisms of sodium channel clustering and its influence on axonal impulse conductionTrafficking regulates the subcellular distribution of voltage-gated sodium channels in primary sensory neuronsNeuroimmune interactions in itch: Do chronic itch, chronic pain, and chronic cough share similar mechanisms?A monoclonal antibody that targets a NaV1.7 channel voltage sensor for pain and itch reliefGlobal Nav1.7 knockout mice recapitulate the phenotype of human congenital indifference to painInhibition of Inactive States of Tetrodotoxin-Sensitive Sodium Channels Reduces Spontaneous Firing of C-Fiber Nociceptors and Produces Analgesia in Formalin and Complete Freund's Adjuvant Models of PainSubtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release.Estradiol upregulates voltage-gated sodium channel 1.7 in trigeminal ganglion contributing to hyperalgesia of inflamed TMJ.Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a.Burning pain: axonal dysfunction in erythromelalgia.Voltage-gated Na+ currents in human dorsal root ganglion neurons.Functional expression of α7-nicotinic acetylcholine receptors by muscle afferent neuronsLinkage between increased nociception and olfaction via a SCN9A haplotypeSodium channel Nav1.7 in vascular myocytes, endothelium, and innervating axons in human skin.Role played by NaV 1.7 channels on thin-fiber muscle afferents in transmitting the exercise pressor reflex.Classifying neuronal subclasses of the cerebellum through constellation pharmacology.EXPRESS: Voltage-dependent sodium (NaV) channels in group IV sensory afferents.Translational pain research: Lessons from genetics and genomics.The role of sodium channels in painful diabetic and idiopathic neuropathy.The Nodes of Ranvier: Molecular Assembly and Maintenance.Fibromyalgia: A Critical and Comprehensive Review.Gain-of-function mutation of a voltage-gated sodium channel NaV1.7 associated with peripheral pain and impaired limb development.Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain.Osteoarthritis-dependent changes in antinociceptive action of Nav1.7 and Nav1.8 sodium channel blockers: An in vivo electrophysiological study in the rat.Antihyperalgesic effects of ProTx-II, a Nav1.7 antagonist, and A803467, a Nav1.8 antagonist, in diabetic mice.A biophysical model examining the role of low-voltage-activated potassium currents in shaping the responses of vestibular ganglion neurons.Saltatory conduction in unmyelinated axons: clustering of Na(+) channels on lipid rafts enables micro-saltatory conduction in C-fibers.Gain-of-function mutations in sodium channel Na(v)1.9 in painful neuropathy.Distribution of TTX-sensitive voltage-gated sodium channels in primary sensory endings of mammalian muscle spindles.DRG Voltage-gated Sodium Channel 1.7 is Up-regulated in Paclitaxel-Induced Neuropathy in Rats and in Humans with Neuropathic Pain.Differential Inhibition of Nav1.7 and Neuropathic Pain by Hybridoma-Produced and Recombinant Monoclonal Antibodies that Target Nav1.7 : Differential activities of Nav1.7-targeting monoclonal antibodies.Sodium Channel Trafficking.Mapping protein interactions of sodium channel NaV1.7 using epitope-tagged gene-targeted mice.Voltage-gated sodium channels: (NaV )igating the field to determine their contribution to visceral nociception.A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.Differential expression of voltage-gated sodium channels in afferent neurons renders selective neural block by ionic direct current.Mechanisms for therapeutic effect of bulleyaconitine A on chronic pain
P2860
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P2860
Expression of Nav1.7 in DRG neurons extends from peripheral terminals in the skin to central preterminal branches and terminals in the dorsal horn.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Expression of Nav1.7 in DRG ne ...... terminals in the dorsal horn.
@en
type
label
Expression of Nav1.7 in DRG ne ...... terminals in the dorsal horn.
@en
prefLabel
Expression of Nav1.7 in DRG ne ...... terminals in the dorsal horn.
@en
P2093
P2860
P356
P1433
P1476
Expression of Nav1.7 in DRG ne ...... terminals in the dorsal horn.
@en
P2093
Joel A Black
Noémie Frézel
Stephen G Waxman
Sulayman D Dib-Hajj
P2860
P2888
P356
10.1186/1744-8069-8-82
P577
2012-11-07T00:00:00Z
P5875
P6179
1033920885