Site-specific DNA cleavage by mammalian DNA topoisomerase II induced by novel flavone and catechin derivatives.
about
(-)-Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerasesBioflavonoids as poisons of human topoisomerase II alpha and II betaDietary polyphenols as topoisomerase II poisons: B ring and C ring substituents determine the mechanism of enzyme-mediated DNA cleavage enhancementDietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemiaDifferential induction of Leishmania donovani bi-subunit topoisomerase I-DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I.Cytotoxicity of dietary flavonoids on different human cancer typesProteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2{middle dot}DNA and Top2{middle dot}RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2)Plant-Based and Plant-Rich Diet Patterns during Gestation: Beneficial Effects and Possible ShortcomingsNatural products as topoisomerase II poisons: effects of thymoquinone on DNA cleavage mediated by human topoisomerase IIαSho-saiko-to: Japanese herbal medicine for protection against hepatic fibrosis and carcinoma.Hormonal treatment for prostate cancer.Activity and interactions of antibiotic and phytochemical combinations against Pseudomonas aeruginosa in vitro.Glycosylated flavones as selective inhibitors of topoisomerase IV.Activity of quinolone CP-115,955 against bacterial and human type II topoisomerases is mediated by different interactions.PC-SPES: a brief overview.Secondary metabolites as DNA topoisomerase inhibitors: A new era towards designing of anticancer drugs.Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases.EGCG regulates the cross-talk between JWA and topoisomerase IIα in non-small-cell lung cancer (NSCLC) cellsOxidative metabolites of curcumin poison human type II topoisomerases.Inhibition of human DNA topoisomerase IIα by two novel ellipticine derivatives.Phytoestrogens: perpetrators or protectors?Effects of Secondary Metabolites from the Fungus Septofusidium berolinense on DNA Cleavage Mediated by Human Topoisomerase IIα.DNA topoisomerase II, genotoxicity, and cancerThe efficacy of topoisomerase II-targeted anticancer agents reflects the persistence of drug-induced cleavage complexes in cellsEpimerization of green tea catechins during brewing does not affect the ability to poison human type II topoisomerases.The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothingTopoisomerase II and leukemia.Phytochemicals as Anticancer and Chemopreventive Topoisomerase II Poisons.Resveratrol mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: a putative mechanism for chemoprevention of cancer.Mechanism of generation of therapy related leukemia in response to anti-topoisomerase II agents.Site-specific anticancer effects of dietary flavonoid quercetin.Flavones inhibit the hexameric replicative helicase RepA.The dietary anticancer agent ellagic acid is a potent inhibitor of DNA topoisomerases in vitro.Free-B-Ring flavonoids as potential lead compounds for colon cancer therapy.Green tea constituents (-)-epigallocatechin-3-gallate (EGCG) and gallic acid induce topoisomerase I- and topoisomerase II-DNA complexes in cells mediated by pyrogallol-induced hydrogen peroxide.Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects.Dietary factors and the risk for acute infant leukemia: evaluating the effects of cocoa-derived flavanols on DNA topoisomerase activity.The epidermal growth factor receptor and human topoisomerases represent potential cellular targets of oligomeric procyanidins.Topoisomerase II enzymes and mutagenicity.Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors.
P2860
Q24627296-E9BAC941-49E4-4AC7-961C-F945F2A93E1DQ24627367-6D2B8E29-3DDD-46B4-8102-B352D391E59EQ24642324-4A8EA6EB-7A3C-4C00-BF16-1FC7132E49DEQ24676660-96640F71-5FFB-4D38-B153-A0D8F00BF15DQ25257476-97035CEC-9120-48B0-ABBE-EC27191B5F72Q27012643-0F9AE04B-10B0-4152-8182-2EDAD275325CQ27683681-04B19574-5C71-4E1E-9F12-D30A26D205F8Q28083165-B8B242A6-1190-4FFF-B9F1-B91A10936B65Q33662233-340C46A9-E511-4CAD-8ECE-C7171F2408C6Q33888088-B5A194ED-EB29-4CB7-A1D1-FFD379758333Q34167174-7B0D3255-C738-41C6-B09A-17D30697AB0AQ34187311-040C95A1-5584-460C-B672-85591175E4EFQ35135912-5BEF6EDD-8168-4CC8-B50A-F5639B847494Q35592636-09C69097-7E4B-413D-AD9F-B5A50D98AE7AQ35604672-52C5BD41-5930-4101-AD31-34DA28FDE255Q35646690-B776BD49-A06F-4856-9526-FF2A305A162AQ35679872-9AFEAFF1-146C-4DD8-85CF-893EC6A838FAQ35687460-7E3B9302-832C-4784-8CC6-72CA7FE5024CQ36520921-22977B86-7D11-4025-971D-CCAC10D132ACQ36669680-A87B15CB-7173-44A1-AFC0-C1E644BE4CBFQ36839782-EB783E47-D023-4405-A8DF-1F823D4B3C59Q36895268-9D1C9E57-B796-4AC2-A3AD-4DD0A2720FC0Q36903197-36BFEFB5-76A5-473A-965F-641FBECB0494Q37061217-D24A1362-A758-4967-8AD0-1FF282403DC5Q37064199-0703A0CC-35E1-4D45-BEAA-71D4A8F4CE83Q37108461-0CE34D9B-7A70-4278-AEC4-3E8E0ECDD858Q37652882-5F25B9F2-744D-4DF6-937D-2A46783774A8Q37658182-B454BFB5-181A-4A59-8AF2-E9C6BCA58764Q37684861-3446D98F-524A-4416-B9D1-F2EBC9A4CD27Q38029323-981A13A3-C1E2-4B9F-9BD4-45E65D8D1533Q38174655-C6A1BC4D-972C-4C22-8C59-91C308DC05CFQ38292604-26D08D71-9167-4144-83F5-FC0EC2003D9AQ38532039-6C3F71D8-7329-4A90-B23F-955C7490153BQ38983517-0B75333B-721B-4D54-8E45-1AFE39049697Q39580025-90069F09-CE7E-4E78-84F9-ACE31AA14541Q39676052-107CAA30-ADD6-4642-90E8-39BE189A12BAQ39713158-7095FC3B-BC02-489C-843D-AFE0B28C5FCBQ40182063-C2C12E02-C8F8-4BE7-8A53-D25DC55C3DC5Q40590105-7C0E8A7E-F5F9-462C-B5FB-5D70B03F8B4CQ40630446-D582773F-CD7C-43B0-95BD-3E6A4784690D
P2860
Site-specific DNA cleavage by mammalian DNA topoisomerase II induced by novel flavone and catechin derivatives.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Site-specific DNA cleavage by ...... vone and catechin derivatives.
@en
Site-specific DNA cleavage by ...... vone and catechin derivatives.
@nl
type
label
Site-specific DNA cleavage by ...... vone and catechin derivatives.
@en
Site-specific DNA cleavage by ...... vone and catechin derivatives.
@nl
prefLabel
Site-specific DNA cleavage by ...... vone and catechin derivatives.
@en
Site-specific DNA cleavage by ...... vone and catechin derivatives.
@nl
P2093
P2860
P356
P1433
P1476
Site-specific DNA cleavage by ...... vone and catechin derivatives.
@en
P2093
P2860
P304
P356
10.1042/BJ2820883
P407
P478
282 ( Pt 3)
P577
1992-03-01T00:00:00Z