Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity. - Wikidata - wikimedia - TriplyDB

Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity.

Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity.

http://www.wikidata.org/entity/Q42260473

about

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells Snaps and mends: DNA breaks and chromosomal translocations The response to and repair of RAG-mediated DNA double-strand breaks Clonal evolution in cancer Gene conversion causing human inherited disease: evidence for involvement of non-B-DNA-forming sequences and recombination-promoting motifs in DNA breakage and repair.Mechanisms of chromosomal rearrangement in the human genome AID-induced remodeling of immunoglobulin genes and B cell fate.AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.Distinct biological subtypes and patterns of genome evolution in lymphoma revealed by circulating tumor DNA.Origin of chromosomal translocations in lymphoid cancer.The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci.Mechanisms promoting translocations in editing and switching peripheral B cells.Widespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination.The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia.Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.Activation-induced cytidine deaminase accelerates clonal evolution in BCR-ABL1-driven B-cell lineage acute lymphoblastic leukemia.The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination DNA methylation and cellular reprogramming Production of IgG autoantibody requires expression of activation-induced deaminase in early-developing B cells in a mouse model of SLE.The AID-induced DNA damage response in chromatin.B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity.Nonhomologous DNA end joining (NHEJ) and chromosomal translocations in humans Fine mapping of V(D)J recombinase mediated rearrangements in human lymphoid malignancies Chromatin Memory in the Development of Human Cancers Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma.Activation-induced cytidine deaminase mediates central tolerance in B cells.Follicular lymphoma: too many reminders for a memory B cell.Human lymphoid translocation fragile zones are hypomethylated and have accessible chromatin.Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes Rapid high-resolution mapping of balanced chromosomal rearrangements on tiling CGH arrays.Clonal origins of ETV6-RUNX1⁺ acute lymphoblastic leukemia: studies in monozygotic twins.Sites of instability in the human TCF3 (E2A) gene adopt G-quadruplex DNA structures in vitro Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia.Translocation capture sequencing: a method for high throughput mapping of chromosomal rearrangements.Immune related genes underpin the evolution of adaptive immunity in jawless vertebrates Spatial organization of the mouse genome and its role in recurrent chromosomal translocations Molecular ontogeny of donor-derived follicular lymphomas occurring after hematopoietic cell transplantation.A structural hierarchy mediated by multiple nuclear factors establishes IgH locus conformation Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity.

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P2860

Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity.

http://www.wikidata.org/entity/Q42260473

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Human chromosomal translocatio ...... lineage and stage specificity.

@en

Human chromosomal translocatio ...... lineage and stage specificity.

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type

label

Human chromosomal translocatio ...... lineage and stage specificity.

@en

Human chromosomal translocatio ...... lineage and stage specificity.

@nl

prefLabel

Human chromosomal translocatio ...... lineage and stage specificity.

@en

Human chromosomal translocatio ...... lineage and stage specificity.

@nl

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J.CELL.2008.10.035

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Human chromosomal translocatio ...... lineage and stage specificity.

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Albert G Tsai

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Chih-Lin Hsieh

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Haihui Lu

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Markus Muschen

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Michael R Lieber

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Sathees C Raghavan

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P2860

Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia.

The human genome browser at UCSC

BLAT--the BLAST-like alignment tool

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

Analysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpoints

XRCC1 protein interacts with one of two distinct forms of DNA ligase III

Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations

Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming

MSH2 deficient mice are viable and susceptible to lymphoid tumours

No requirement for V(D)J recombination in p53-deficient thymic lymphoma

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10.1016/J.CELL.2008.10.035

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