Cell cycle-dependent accumulation in vivo of transposition-competent complexes between recombination signal ends and full-length RAG proteins.
about
A PHD finger motif in the C terminus of RAG2 modulates recombination activityRequirement for ubiquitin conjugation and 26S proteasome activity at an early stage in V(D)J recombinationMobilization of RAG-generated signal ends by transposition and insertion in vivoCoupling of V(D)J recombination to the cell cycle suppresses genomic instability and lymphoid tumorigenesis.DNA cleavage activity of the V(D)J recombination protein RAG1 is autoregulated.New concepts in the regulation of an ancient reaction: transposition by RAG1/RAG2.Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases.A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement.Pre-TCR-induced beta-catenin facilitates traversal through beta-selectionSustained expression of pre-TCR induced beta-catenin in post-beta-selection thymocytes blocks T cell developmentInitial stages of V(D)J recombination: the organization of RAG1/2 and RSS DNA in the postcleavage complex.Temporal and spatial regulation of V(D)J recombination: interactions of extrinsic factors with the RAG complex.New insights into the evolutionary origins of the recombination-activating gene proteins and V(D)J recombination.The MRE11-RAD50-XRS2 complex, in addition to other non-homologous end-joining factors, is required for V(D)J joining in yeast.
P2860
Q28592944-382979A6-467C-4740-B57B-0DB51E19D75FQ33695537-D7A1722F-E010-4234-A5BD-502F018A6736Q34353659-7E1E3434-C347-4257-8AB3-6F9EE4038C81Q34760276-00F6A915-FBE7-44B6-B633-CFA3919991D7Q35663928-5C1408BB-AF83-415A-A84E-86D9CD0549D2Q35830448-801FCFA9-2B86-4A06-93CA-B461F983A1B7Q36827351-3E99D25C-B7A2-4F54-98F1-BBBFFDE5E7C9Q37013832-860CC5DA-34DF-4316-9ED6-76E66A96161BQ37132613-810EE102-FD53-489D-A63D-81B59BCEE864Q37239537-A84BEB40-8B40-47D4-9643-851AE14B65C0Q37313793-EFE62B72-2155-4BFC-B758-8D570CBBF33FQ37592212-998664BD-17D2-4E37-87A6-9CF91A95E557Q39038472-5FDEBC36-59F8-43CA-9862-9A57F1A73153Q54676348-AAC42B0C-1227-4159-B6B3-28CA019251AF
P2860
Cell cycle-dependent accumulation in vivo of transposition-competent complexes between recombination signal ends and full-length RAG proteins.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Cell cycle-dependent accumulat ...... and full-length RAG proteins.
@en
Cell cycle-dependent accumulat ...... and full-length RAG proteins.
@nl
type
label
Cell cycle-dependent accumulat ...... and full-length RAG proteins.
@en
Cell cycle-dependent accumulat ...... and full-length RAG proteins.
@nl
prefLabel
Cell cycle-dependent accumulat ...... and full-length RAG proteins.
@en
Cell cycle-dependent accumulat ...... and full-length RAG proteins.
@nl
P2860
P356
P1476
Cell cycle-dependent accumulat ...... and full-length RAG proteins.
@en
P2093
Stephen Desiderio
P2860
P304
P356
10.1074/JBC.M311219200
P407
P577
2003-12-04T00:00:00Z