Specific targeting of cytosine methylation to DNA sequences in vivo.
about
Enabling functional genomics with genome engineeringEpigenome engineering in cancer: fairytale or a realistic path to the clinic?The epigenome: the next substrate for engineeringModular system for the construction of zinc-finger libraries and proteins.Heterodimeric DNA methyltransferases as a platform for creating designer zinc finger methyltransferases for targeted DNA methylation in cells.Cell-specific DNA methylation patterns of retina-specific genesTargeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins.Writing and rewriting the epigenetic code of cancer cells: from engineered proteins to small moleculesColonic mucosal DNA methylation, immune response, and microbiome patterns in Toll-like receptor 2-knockout miceDirected evolution of improved zinc finger methyltransferases.Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes.DNA methylation in schizophrenia: progress and challenges of epigenetic studiesRegulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.The triple helix: 50 years later, the outcome.Understanding posttraumatic stress disorder: insights from the methylome.Site-specific methylated reporter constructs for functional analysis of DNA methylation.Synthetic epigenetics-towards intelligent control of epigenetic states and cell identityRewriting DNA Methylation Signatures at Will: The Curable Genome Within Reach?Organomegaly and tumors in transgenic mice with targeted expression of HpaII methyltransferase in smooth muscle cellsTargeted DNA methylation by a DNA methyltransferase coupled to a triple helix forming oligonucleotide to down-regulate the epithelial cell adhesion molecule.Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation.An engineered split M.HhaI-zinc finger fusion lacks the intended methyltransferase specificity.A directed evolution design of a GCG-specific DNA hemimethylase.Heritable gene repression through the action of a directed DNA methyltransferase at a chromosomal locus.Epigenetic editing: How cutting-edge targeted epigenetic modification might provide novel avenues for autoimmune disease therapy.Designing Epigenome Editors: Considerations of Biochemical and Locus Specificities.
P2860
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P2860
Specific targeting of cytosine methylation to DNA sequences in vivo.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Specific targeting of cytosine methylation to DNA sequences in vivo.
@en
Specific targeting of cytosine methylation to DNA sequences in vivo.
@nl
type
label
Specific targeting of cytosine methylation to DNA sequences in vivo.
@en
Specific targeting of cytosine methylation to DNA sequences in vivo.
@nl
prefLabel
Specific targeting of cytosine methylation to DNA sequences in vivo.
@en
Specific targeting of cytosine methylation to DNA sequences in vivo.
@nl
P2860
P356
P1476
Specific targeting of cytosine methylation to DNA sequences in vivo.
@en
P2093
Alexander E Smith
Kevin G Ford
P2860
P304
P356
10.1093/NAR/GKL1053
P407
P577
2006-12-20T00:00:00Z