Pharmacological targeting the ATR-CHK1-WEE1 axis involves balancing cell growth stimulation and apoptosis.
about
Targeting the Checkpoint to Kill Cancer CellsCo-inhibition of polo-like kinase 1 and Aurora kinases promotes mitotic catastrophe.Pharmacological inactivation of CHK1 and WEE1 induces mitotic catastrophe in nasopharyngeal carcinoma cells.ATR-Chk1 signaling inhibition as a therapeutic strategy to enhance cisplatin chemosensitivity in urothelial bladder cancer.Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitorsHuman CDK18 promotes replication stress signaling and genome stability.HPLC-UV method for simultaneous determination of MK-1775 and AZD-7762 in both acetonitrile-aqueous solution and mouse plasma.WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner.ATR/CHK1 inhibitors and cancer therapy.Suppression of Sirt1 sensitizes lung cancer cells to WEE1 inhibitor MK-1775-induced DNA damage and apoptosis.Wnt pathway is involved in 5-FU drug resistance of colorectal cancer cells
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Pharmacological targeting the ATR-CHK1-WEE1 axis involves balancing cell growth stimulation and apoptosis.
description
2014 nî lūn-bûn
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name
Pharmacological targeting the ...... wth stimulation and apoptosis.
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Pharmacological targeting the ...... wth stimulation and apoptosis.
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type
label
Pharmacological targeting the ...... wth stimulation and apoptosis.
@en
Pharmacological targeting the ...... wth stimulation and apoptosis.
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prefLabel
Pharmacological targeting the ...... wth stimulation and apoptosis.
@en
Pharmacological targeting the ...... wth stimulation and apoptosis.
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P2860
P356
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Pharmacological targeting the ...... owth stimulation and apoptosis
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P2093
Randy Y C Poon
Wing Yu Man
P2860
P304
10546-10557
P356
10.18632/ONCOTARGET.2508
P407
P577
2014-11-01T00:00:00Z