NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin.
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Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancerUnderstanding the human health effects of chemical mixtures.Interaction of the molecular chaperone Hsp70 with human NAD(P)H:quinone oxidoreductase 1NQO1 C609T polymorphism and colorectal cancer susceptibility: a meta-analysisCrystal structure of quinone reductase 2 in complex with resveratrolRegulation of Nrf2-an updateNrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 geneVariation in genes relevant to aromatic hydrocarbon metabolism and the risk of adult brain tumors.NQO1 stabilizes p53 through a distinct pathway.High-throughput library screening identifies two novel NQO1 inducers in human lung cellsA functional NQO1 609C>T polymorphism and risk of gastrointestinal cancers: a meta-analysis.Inactivation of the quinone oxidoreductases NQO1 and NQO2 strongly elevates the incidence and multiplicity of chemically induced skin tumors.Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1.A functional NQO1 609C>T polymorphism and risk of hepatocellular carcinoma in a Chinese population.Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing.NRH:quinone oxidoreductase 2-deficient mice are highly susceptible to radiation-induced B-cell lymphomasEffects of heme oxygenase-1 on induction and development of chemically induced squamous cell carcinoma in mice.High expression of NQO1 is associated with poor prognosis in serous ovarian carcinoma.Role of gene knockout and transgenic mice in the study of xenobiotic metabolism.Quinone reductases multitasking in the metabolic world.Evidence from ESI-MS for NQO1-catalyzed reduction of estrogen ortho-quinonesAssociation between gene expression of metabolizing enzymes and esophageal squamous cell carcinomas in China.Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction.Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to radiation-induced myeloproliferative disease.Activation of NQO1 in NQO1*2 polymorphic human leukemic HL-60 cells by diet-derived sulforaphaneGenetic polymorphisms of NQO1, CYP1A1 and TPMT and susceptibility to acute lymphoblastic leukemia in a Tunisian population.Stress-induced NQO1 controls stability of C/EBPα against 20S proteasomal degradation to regulate p63 expression with implications in protection against chemical-induced skin cancer.Candidate dietary phytochemicals modulate expression of phase II enzymes GSTP1 and NQO1 in human lung cellsEndogenous ω-3 Fatty Acid Production by fat-1 Transgene and Topically Applied Docosahexaenoic Acid Protect against UVB-induced Mouse Skin Carcinogenesis.Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity.Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems.Evaluation of the effect of beetroot juice on DMBA-induced damage in liver and mammary gland of female Sprague-Dawley rats.The effect of cloudy apple juice on hepatic and mammary gland phase I and II enzymes induced by DMBA in female Sprague-Dawley rats.Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis.Genetic association of Glutathione peroxidase-1 (GPx-1) and NAD(P)H:Quinone Oxidoreductase 1(NQO1) variants and their association of CAD in patients with type-2 diabetes.
P2860
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P2860
NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
NAD(P)H:quinone oxidoreductase ...... carcinogenesis in mouse skin.
@en
NAD(P)H:quinone oxidoreductase ...... carcinogenesis in mouse skin.
@nl
type
label
NAD(P)H:quinone oxidoreductase ...... carcinogenesis in mouse skin.
@en
NAD(P)H:quinone oxidoreductase ...... carcinogenesis in mouse skin.
@nl
prefLabel
NAD(P)H:quinone oxidoreductase ...... carcinogenesis in mouse skin.
@en
NAD(P)H:quinone oxidoreductase ...... carcinogenesis in mouse skin.
@nl
P2093
P2860
P356
P1476
NAD(P)H:quinone oxidoreductase ...... carcinogenesis in mouse skin.
@en
P2093
P2860
P304
P356
10.1093/JNCI/93.15.1166
P407
P577
2001-08-01T00:00:00Z