Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems. - Wikidata - wikimedia - TriplyDB

Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems.

Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems.

http://www.wikidata.org/entity/Q44279157

about

Implications of NQO1 in cancer therapy Quercetin as an Emerging Anti-Melanoma Agent: A Four-Focus Area Therapeutic Development Strategy NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73 Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyrene Impairment of antioxidant defenses as a contributor to arsenite-induced cell transformation Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2.ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphism In vitro gene regulatory networks predict in vivo function of liver Relationships between metabolic and non-metabolic susceptibility factors in benzene toxicity.K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts.Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.NAD(P)H:quinone oxidoreductase 1 is induced by progesterone in cardiomyocytes.Inactivation of the quinone oxidoreductases NQO1 and NQO2 strongly elevates the incidence and multiplicity of chemically induced skin tumors.P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1 Ubiquitin proteasomal pathway mediated degradation of p53 in melanoma Prognostic significance of NQO1 expression in intrahepatic cholangiocarcinoma.Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging Role of gene knockout and transgenic mice in the study of xenobiotic metabolism.A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone.Quinone reductases multitasking in the metabolic world.Excess transmission of the NAD(P)H:quinone oxidoreductase 1 (NQO1) C609T polymorphism in families of children with acute lymphoblastic leukemia.Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension.Versatile functions of p53 protein in multicellular organisms Artemis is a negative regulator of p53 in response to oxidative stress Activation of NQO1 in NQO1*2 polymorphic human leukemic HL-60 cells by diet-derived sulforaphane Redox modulation of p53: mechanisms and functional significance.NAD(P)H: quinone oxidoreductase 1 and its potential protective role in cardiovascular diseases and related conditions.Using DNA devices to track anticancer drug activity.DNA damage signalling barrier, oxidative stress and treatment-relevant DNA repair factor alterations during progression of human prostate cancer.NQO1 suppresses NF-κB-p300 interaction to regulate inflammatory mediators associated with prostate tumorigenesis.Genetic polymorphisms of NQO1, CYP1A1 and TPMT and susceptibility to acute lymphoblastic leukemia in a Tunisian population.Up-regulation of plasma membrane-associated redox activities in neuronal cells lacking functional mitochondria.Can dicoumarol be used as a gonad-safe anticancer agent: an in vitro and in vivo experimental study.The two common polymorphic forms of human NRH-quinone oxidoreductase 2 (NQO2) have different biochemical properties.Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism.Benzene toxicity: The role of the susceptibility factor NQO1 in bone marrow endothelial cell signaling and function.Clonal haemopoiesis may occur after conventional chemotherapy and is associated with accelerated telomere shortening and defects in the NQO1 pathway; possible mechanisms leading to an increased risk of t-AML/MDS.Genetic polymorphism of NAD(P)H:quinone oxidoreductase is associated with an increased risk of infant acute lymphoblastic leukemia without MLL gene rearrangements.NAD(P)H:quinone oxidoreductase 1 NQO1*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer.

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P2860

Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems.

http://www.wikidata.org/entity/Q44279157

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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name

Interaction of human NAD

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Interaction of human NAD(P)H:q ...... n cells and cell-free systems.

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type

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Interaction of human NAD

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Interaction of human NAD(P)H:q ...... n cells and cell-free systems.

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prefLabel

Interaction of human NAD

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Interaction of human NAD(P)H:q ...... n cells and cell-free systems.

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P1433

Journal of Biological Chemistry

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Interaction of human NAD(P)H:q ...... n cells and cell-free systems.

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P2093

Adil Anwar

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David Ross

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David Siegel

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Donna Dehn

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Jadwiga K Kepa

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Luo Jia Tang

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P2860

Mdm2 promotes the rapid degradation of p53

Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity

Regulation of JNK signaling by GSTp

Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.

ZBP-89 promotes growth arrest through stabilization of p53

Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches

Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity

Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus

Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

Interaction of the molecular chaperone Hsp70 with human NAD(P)H:quinone oxidoreductase 1

P304

10368-10373

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scholarly article

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10.1074/JBC.M211981200

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12

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278

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Jennifer A. Pietenpol

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2003-01-14T00:00:00Z

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10950032

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12529318

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