Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain.
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The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and Abeta generation in vivo.ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bileEffects of specific multi-nutrient enriched diets on cerebral metabolism, cognition and neuropathology in AβPPswe-PS1dE9 miceSpecific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function.Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease.Analysis of oxysterols by electrospray tandem mass spectrometry.Hypertension, cerebrovascular impairment, and cognitive decline in aged AβPP/PS1 miceCholesterol metabolism changes under long-term dietary restrictions while the cholesterol homeostasis remains unaffected in the cortex and hippocampus of aging ratsSeladin-1 as a target of estrogen receptor activation in the brain: a new gene for a rather old story?Significance of sterol structural specificity. Desmosterol cannot replace cholesterol in lipid rafts.Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.Reduced cholesterol is associated with the depressive-like behavior in rats through modulation of the brain 5-HT1A receptor.Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects.Oxidation of 7-dehydrocholesterol and desmosterol by human cytochrome P450 46A1.Analysis of bioactive oxysterols in newborn mouse brain by LC/MS.Cholesterol metabolism in the brain: importance of 24S-hydroxylation.Liquid chromatography-mass spectrometry utilizing multi-stage fragmentation for the identification of oxysterols.A Dietary Treatment Improves Cerebral Blood Flow and Brain Connectivity in Aging apoE4 MiceLiver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementiaMetabolomics and metabolite profiling: past heroes and future developments.Vitamin D3 effects on lipids differ in statin and non-statin-treated humans: superiority of free 25-OH D levels in detecting relationshipsAge-dependent increase in desmosterol restores DRM formation and membrane-related functions in cholesterol-free DHCR24-/- mice.Brain sterol dysregulation in sporadic AD and MCI: relationship to heme oxygenase-1.The effect of APOE genotype on brain levels of oxysterols in young and old human APOE epsilon2, epsilon3 and epsilon4 knock-in mice.ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo.Selective sterol accumulation in ABCG5/ABCG8-deficient mice.Dietary intake of plant sterols stably increases plant sterol levels in the murine brain.Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosisImpact of a multi-nutrient diet on cognition, brain metabolism, hemodynamics, and plasticity in apoE4 carrier and apoE knockout mice.Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice.Targeted lipidomic analysis of oxysterols in the embryonic central nervous system.Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice.Effect of rapeseed oil-derived plant sterol and stanol esters on atherosclerosis parameters in cholesterol-challenged heterozygous Watanabe heritable hyperlipidaemic rabbits.Adaptation of neuronal cells to chronic oxidative stress is associated with altered cholesterol and sphingolipid homeostasis and lysosomal function.Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8.Reductions in cholesterol and synaptic markers in association cortex in mood disorders.Regulation of hippocampal cholesterol metabolism by apoE and environmental stimulation.Limited daily feeding and intermittent feeding have different effects on regional brain energy homeostasis during aging.Increased plant sterol and stanol levels in brain of Watanabe rabbits fed rapeseed oil derived plant sterol or stanol esters.Physiologically regulated transgenic ABCA1 does not reduce amyloid burden or amyloid-beta peptide levels in vivo.
P2860
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P2860
Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Profile of cholesterol-related ...... rotein transgenic mouse brain.
@en
Profile of cholesterol-related ...... rotein transgenic mouse brain.
@nl
type
label
Profile of cholesterol-related ...... rotein transgenic mouse brain.
@en
Profile of cholesterol-related ...... rotein transgenic mouse brain.
@nl
prefLabel
Profile of cholesterol-related ...... rotein transgenic mouse brain.
@en
Profile of cholesterol-related ...... rotein transgenic mouse brain.
@nl
P2093
P50
P1476
Profile of cholesterol-related ...... rotein transgenic mouse brain.
@en
P2093
Andreas Brzezinka
Dieter Lütjohann
Dorothee Abramowski
Esther Barth
Klaus von Bergmann
Thomas A Bayer
P304
P356
10.1194/JLR.M200071-JLR200
P577
2002-07-01T00:00:00Z