P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1

P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1

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http://www.wikidata.org/entity/Q34390794
Mutant p53 Drives Cancer by Subverting Multiple Tumor Suppression PathwaysInhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathwayQuercetin as an Emerging Anti-Melanoma Agent: A Four-Focus Area Therapeutic Development StrategyNAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotectorA mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73An NQO1-initiated and p53-independent apoptotic pathway determines the anti-tumor effect of tanshinone IIA against non-small cell lung cancerEts1 is an effector of protein kinase Calpha in cancer cells.NAD(P)H: quinone oxidoreductase 1 deficiency conjoint with marginal vitamin C deficiency causes cigarette smoke induced myelodysplastic syndromes.DNA-binding and transactivation activities are essential for TAp63 protein degradation.Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.Cytotoxic effect of a non-peptidic small molecular inhibitor of the p53-HDM2 interaction on tumor cells.Ell3 stabilizes p53 following CDDP treatment via its effects on ubiquitin-dependent and -independent proteasomal degradation pathways in breast cancer cellsHarmonic oscillations in homeostatic controllers: Dynamics of the p53 regulatory system.Control of stability of cyclin D1 by quinone reductase 2 in CWR22Rv1 prostate cancer cells.Aurora-A kinase interacting protein 1 (AURKAIP1) promotes Aurora-A degradation through an alternative ubiquitin-independent pathway.Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D.c-Fos proteasomal degradation is activated by a default mechanism, and its regulation by NAD(P)H:quinone oxidoreductase 1 determines c-Fos serum response kinetics.
P2860

P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1

Item
http://www.wikidata.org/entity/Q34390794
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
P53 hot-spot mutants are resis ...... on by increased binding to NAD
@nl
P53 hot-spot mutants are resis ...... D(P)H:quinone oxidoreductase 1
@ast
P53 hot-spot mutants are resis ...... D(P)H:quinone oxidoreductase 1
@en
type
label
P53 hot-spot mutants are resis ...... on by increased binding to NAD
@nl
P53 hot-spot mutants are resis ...... D(P)H:quinone oxidoreductase 1
@ast
P53 hot-spot mutants are resis ...... D(P)H:quinone oxidoreductase 1
@en
prefLabel
P53 hot-spot mutants are resis ...... on by increased binding to NAD
@nl
P53 hot-spot mutants are resis ...... D(P)H:quinone oxidoreductase 1
@ast
P53 hot-spot mutants are resis ...... D(P)H:quinone oxidoreductase 1
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
P53 hot-spot mutants are resis ...... D(P)H:quinone oxidoreductase 1
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932