about
Disruption of maternal DNA repair increases sperm-derived chromosomal aberrationsMutS homologue hMSH4: interaction with eIF3f and a role in NHEJ-mediated DSB repairPromiscuous drugs compared to selective drugs (promiscuity can be a virtue)Two distinct cytokinesis pathways drive trypanosome cell division initiation from opposite cell ends.Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Modulation of DNA end joining by nuclear proteinsDNA ligases I and III cooperate in alternative non-homologous end-joining in vertebratesThe human DNA ends proteome uncovers an unexpected entanglement of functional pathwaysMMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endingsRAG2 mutants alter DSB repair pathway choice in vivo and illuminate the nature of 'alternative NHEJ'.Inhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs)TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends.Double-strand breaks repair in lymphoblastoid cell lines from sisters discordant for breast cancer from the New York site of the BCFRDNA-PKcs deficiency leads to persistence of oxidatively induced clustered DNA lesions in human tumor cells.Coincident In Vitro Analysis of DNA-PK-Dependent and -Independent Nonhomologous End Joining.Choosing the right path: does DNA-PK help make the decision?DNA damage response and DNA repair - dog as a model?Homozygous deficiency of ubiquitin-ligase ring-finger protein RNF168 mimics the radiosensitivity syndrome of ataxia-telangiectasia.Saccharomyces cerevisiae Sae2- and Tel1-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining.Linking double-stranded DNA breaks to the recombination activating gene complex directs repair to the nonhomologous end-joining pathwayKu heterodimer-independent end joining in Trypanosoma brucei cell extracts relies upon sequence microhomology.Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks.Single-cell microarray enables high-throughput evaluation of DNA double-strand breaks and DNA repair inhibitors.DNA double-strand break repair and development.Mechanisms of leukemia translocationsGamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatinScaffold attachment factor A (SAF-A) and Ku temporally regulate repair of radiation-induced clustered genome lesionsThe role of PARP1 in the DNA damage response and its application in tumor therapy.Pathways for genome integrity in G2 phase of the cell cycle.The mutagenic potential of non-homologous end joining in the absence of the NHEJ core factors Ku70/80, DNA-PKcs and XRCC4-LigIV.Conformational transitions of proteins engaged in DNA double-strand break repair, analysed by tryptophan fluorescence emission and FRET.Chlorpyrifos Induces MLL Translocations Through Caspase 3-Dependent Genomic Instability and Topoisomerase II Inhibition in Human Fetal Liver Hematopoietic Stem Cells.Interleukin-4 enhances PARP-dependent DNA repair activity in vitroDevelopment of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells.Defective DNA double-strand break repair in pediatric systemic lupus erythematosus.The nucleo-shuttling of the ATM protein as a basis for a novel theory of radiation response: resolution of the linear-quadratic model.Visualization of a DNA-PK/PARP1 complex.Histone H1 functions as a stimulatory factor in backup pathways of NHEJPolq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development.ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Backup pathways of NHEJ are suppressed by DNA-PK.
@en
Backup pathways of NHEJ are suppressed by DNA-PK.
@nl
type
label
Backup pathways of NHEJ are suppressed by DNA-PK.
@en
Backup pathways of NHEJ are suppressed by DNA-PK.
@nl
prefLabel
Backup pathways of NHEJ are suppressed by DNA-PK.
@en
Backup pathways of NHEJ are suppressed by DNA-PK.
@nl
P2093
P2860
P356
P1476
Backup pathways of NHEJ are suppressed by DNA-PK.
@en
P2093
Bustanur Rosidi
George Iliakis
Huichen Wang
Minli Wang
Ronel Perrault
P2860
P304
P356
10.1002/JCB.20104
P577
2004-07-01T00:00:00Z