Activation of protooncogene c-jun by the X protein of hepatitis B virus.
about
Akt augments the oncogenic potential of the HBx protein of hepatitis B virus by phosphorylationHuman RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivationUnderstanding the role of PIN1 in hepatocellular carcinomaGene expression profile analysis of human hepatocellular carcinoma using SAGE and LongSAGE.Human hepatitis B virus mutants: significance of molecular changes.Hepatitis B virus HBx protein deregulates cell cycle checkpoint controlsDifferent regions of hepatitis B virus X protein are required for enhancement of bZip-mediated transactivation versus transrepression.Role of NF-kappaB and myc proteins in apoptosis induced by hepatitis B virus HBx protein.Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma.Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells.Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascadeHepatitis B virus HBx protein activates transcription factor NF-kappaB by acting on multiple cytoplasmic inhibitors of rel-related proteinsHepatitis B virus HBx protein induces transcription factor AP-1 by activation of extracellular signal-regulated and c-Jun N-terminal mitogen-activated protein kinasesThe hepatitis B virus X gene induces p53-mediated programmed cell death.Establishment and characterization of four human hepatocellular carcinoma cell lines containing hepatitis B virus DNAThe hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors.Hepatitis B Virus X Protein Driven Alpha Fetoprotein Expression to Promote Malignant Behaviors of Normal Liver Cells and Hepatoma CellsThe transcription factor c-JUN/AP-1 promotes HBV-related liver tumorigenesis in miceRegulation of transforming growth factor-beta 1 expression by the hepatitis B virus (HBV) X transactivator. Role in HBV pathogenesis.A truncated mutant (residues 58-140) of the hepatitis B virus X protein retains transactivation function.Targeted therapy of hepatocellular cancer.Hepatitis B virus X gene and hepatocarcinogenesis.Molecular targeted therapy for hepatocellular carcinoma: current and future.An internal segment (residues 58-119) of the hepatitis B virus X protein is sufficient to activate MAP kinase pathways in mouse liver.Induction of the DNA-binding activity of c-jun/c-fos heterodimers by the hepatitis B virus transactivator pXHepatitis B virus surface (S) transactivator with DNA-binding properties.HBx-DNA probe preparation and its application in study of hepatocarcinogenesis.Echovirus 1 replication, not only virus binding to its receptor, VLA-2, is required for the induction of cellular immediate-early genes.The X protein of hepatitis B virus coactivates potent activation domains.Differential effects on apoptosis induction in hepatocyte lines by stable expression of hepatitis B virus X protein.Induction of cell cycle progression by hepatitis B virus HBx gene expression in quiescent mouse fibroblasts.Expression of c-Myc, c-Fos, and c-jun in hepatocellular carcinoma.Hepatitis B virus X protein differentially activates RAS-RAF-MAPK and JNK pathways in X-transforming versus non-transforming AML12 hepatocytes.Hepatitis B virus X mutants derived from human hepatocellular carcinoma retain the ability to abrogate p53-induced apoptosis.Induction of apoptosis by the transactivating domains of the hepatitis B virus X gene leads to suppression of oncogenic transformation of primary rat embryo fibroblasts.Hepatitis B virus HBx protein activation of cyclin A-cyclin-dependent kinase 2 complexes and G1 transit via a Src kinase pathway.Differential immediate early gene expression in conditional hepatitis B virus pX-transforming versus nontransforming hepatocyte cell lines.The hepatitis B virus X protein enhances the DNA binding potential and transcription efficacy of bZip transcription factors.Human hepatitis B virus enhancer 1 is responsive to human interleukin-6.Hepatitis B virus transcriptional activators: mechanisms and possible role in oncogenesis.
P2860
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P2860
Activation of protooncogene c-jun by the X protein of hepatitis B virus.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh-hant
name
Activation of protooncogene c-jun by the X protein of hepatitis B virus.
@en
Activation of protooncogene c-jun by the X protein of hepatitis B virus.
@nl
type
label
Activation of protooncogene c-jun by the X protein of hepatitis B virus.
@en
Activation of protooncogene c-jun by the X protein of hepatitis B virus.
@nl
prefLabel
Activation of protooncogene c-jun by the X protein of hepatitis B virus.
@en
Activation of protooncogene c-jun by the X protein of hepatitis B virus.
@nl
P2093
P356
P1433
P1476
Activation of protooncogene c-jun by the X protein of hepatitis B virus.
@en
P2093
P304
P356
10.1006/VIRO.1993.1041
P407
P577
1993-01-01T00:00:00Z