Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy.
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"Inflammaging" as a Druggable Target: A Senescence-Associated Secretory Phenotype-Centered View of Type 2 DiabetesTargeting Mitochondria and Reactive Oxygen Species-Driven Pathogenesis in Diabetic NephropathyMitochondrial autophagy involving renal injury and aging is modulated by caloric intake in aged rat kidneysHyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy.Regular exercise participation improves genomic stability in diabetic patients: an exploratory study to analyse telomere length and DNA damage.The effects of fucodian on senescence are controlled by the p16INK4a-pRb and p14Arf-p53 pathways in hepatocellular carcinoma and hepatic cell lines.Quantitative digital in situ senescence-associated β-galactosidase assayChronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice.Transition of kidney tubule cells to a senescent phenotype in early experimental diabetes.CYP24A1 exacerbated activity during diabetes contributes to kidney tubular apoptosis via caspase-3 increased expression and activation.The proximal tubule in the pathophysiology of the diabetic kidney.Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation.In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells.Ghrelin protects against renal damages induced by angiotensin-II via an antioxidative stress mechanism in mice.Shear Stress-Induced Alteration of Epithelial Organization in Human Renal Tubular CellsCellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity.Leukocyte telomere length and diabetes status, duration, and control: the 1999-2002 National Health and Nutrition Examination Survey.Association of relative telomere length with progression of chronic kidney disease in two cohorts: effect modification by smoking and diabetesUrinary MicroRNA Profiling Predicts the Development of Microalbuminuria in Patients with Type 1 Diabetes.Can we target tubular damage to prevent renal function decline in diabetes?Renal function in diabetic disease models: the tubular system in the pathophysiology of the diabetic kidney.Leukocyte telomere length and mortality risk in patients with type 2 diabetes.Pathophysiology of the diabetic kidney.Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD.The influence of the telomere-telomerase system on diabetes mellitus and its vascular complications.Renal Aging: Causes and Consequences.Cellular senescence in renal ageing and disease.Pathophysiological Fundamentals of Diabetic Cardiomyopathy.Regulating Autophagy as a Therapeutic Target for Diabetic Nephropathy.The Telomeric Complex and Metabolic DiseaseTelomere length in atherosclerosis and diabetes.Sulodexide Protects Renal Tubular Epithelial Cells from Oxidative Stress-Induced Injury via Upregulating Klotho Expression at an Early Stage of Diabetic Kidney DiseaseP16INK4a Positive Cells in Human Skin Are Indicative of Local Elastic Fiber Morphology, Facial Wrinkling, and Perceived Age.p21(WAF1/CIP1) Expression is Differentially Regulated by Metformin and Rapamycin.Short-term High Dose of Quercetin and Resveratrol Alters Aging Markers in Human Kidney Cells.Add-on aliskiren elicits stronger renoprotection than high-dose valsartan in type 2 diabetic KKAy mice that do not respond to low-dose valsartan.Cellular senescence, senescence-associated secretory phenotype, and chronic kidney diseaseFeline chronic kidney disease is associated with shortened telomeres and increased cellular senescence.Short-term sustained hyperglycaemia fosters an archetypal senescence-associated secretory phenotype in endothelial cells and macrophages.Toll-like receptor-4 signaling mediates inflammation and tissue injury in diabetic nephropathy.
P2860
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P2860
Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy.
@en
Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy.
@nl
type
label
Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy.
@en
Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy.
@nl
prefLabel
Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy.
@en
Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy.
@nl
P2093
P1476
Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy.
@en
P2093
Annamaria Ferraris
Barbara Villaggio
Daniela Verzola
Fabio Gianiorio
Fanny Tosetti
Franco Ferrario
Giacomo Deferrari
Gianfranco Gaetani
Maria Teresa Gandolfo
Mariano Mji
P304
P356
10.1152/AJPRENAL.90302.2008
P577
2008-09-03T00:00:00Z