Strategies for the in vitro evolution of protein function: enzyme evolution by random recombination of improved sequences.
about
Evolvability is a selectable traitExploring protein fitness landscapes by directed evolutionA structural view of evolutionary divergenceDirected evolution converts subtilisin E into a functional equivalent of thermitaseThe virtue of innovation: innovation through the lenses of biological evolutionDNA shuffling method for generating highly recombined genes and evolved enzymes.Investigating and Engineering Enzymes by Genetic Selection.Chemical and biochemical strategies for the randomization of protein encoding DNA sequences: library construction methods for directed evolution.A quantitative, high-throughput screen for protein stability.High efficiency family shuffling based on multi-step PCR and in vivo DNA recombination in yeast: statistical and functional analysis of a combinatorial library between human cytochrome P450 1A1 and 1A2Library analysis of SCHEMA-guided protein recombination.Directed evolution strategies for enantiocomplementary haloalkane dehalogenases: from chemical waste to enantiopure building blocks.Molecular evolution by staggered extension process (StEP) in vitro recombination.Random-priming in vitro recombination: an effective tool for directed evolution.Heterologous overexpression of a mutant termite cellulase gene in Escherichia coli by DNA shuffling of four orthologous parental cDNAs.IPRO: an iterative computational protein library redesign and optimization procedureRevealing biases inherent in recombination protocols.Simultaneous improvement of catalytic activity and thermal stability of tyrosine phenol-lyase by directed evolution.Directed evolution and structural prediction of cellobiohydrolase II from the thermophilic fungus Chaetomium thermophilum.Perspective: transposable elements, parasitic DNA, and genome evolution.A hierarchical approach to protein molecular evolutionExploring the potential of xenobiotic-metabolising enzymes as biocatalysts: evolving designer catalysts from polyfunctional cytochrome P450 enzymes.Delineation of an evolutionary salvage pathway by compensatory mutations of a defective lysozyme.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Evolution of a cytokine using DNA family shuffling.Scientific discovery as a combinatorial optimisation problem: how best to navigate the landscape of possible experiments?Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling.Improving phytase enzyme activity in a recombinant phyA mutant phytase from Aspergillus niger N25 by error-prone PCR.The effect of population structure on the rate of evolution.
P2860
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P2860
Strategies for the in vitro evolution of protein function: enzyme evolution by random recombination of improved sequences.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Strategies for the in vitro ev ...... ination of improved sequences.
@en
Strategies for the in vitro ev ...... ination of improved sequences.
@nl
type
label
Strategies for the in vitro ev ...... ination of improved sequences.
@en
Strategies for the in vitro ev ...... ination of improved sequences.
@nl
prefLabel
Strategies for the in vitro ev ...... ination of improved sequences.
@en
Strategies for the in vitro ev ...... ination of improved sequences.
@nl
P2093
P356
P1476
Strategies for the in vitro ev ...... ination of improved sequences.
@en
P2093
P304
P356
10.1006/JMBI.1997.1252
P407
P577
1997-09-01T00:00:00Z