Pure manganese(III) 5,10,15,20-tetrakis(4-benzoic acid)porphyrin (MnTBAP) is not a superoxide dismutase mimic in aqueous systems: a case of structure-activity relationship as a watchdog mechanism in experimental therapeutics and biology.
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The copper chelator ATN-224 induces peroxynitrite-dependent cell death in hematological malignanciesSOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathwaysMn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathwaysIntegrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis.Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potentialRational design of superoxide dismutase (SOD) mimics: the evaluation of the therapeutic potential of new cationic Mn porphyrins with linear and cyclic substituents.Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.Effect of lipophilicity of Mn (III) ortho N-alkylpyridyl- and diortho N, N'-diethylimidazolylporphyrins in two in-vitro models of oxygen and glucose deprivation-induced neuronal death.Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimicsAn educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins--From superoxide dismutation to H2O2-driven pathways.HPLC study of oxidation products of hydroethidine in chemical and biological systems: ramifications in superoxide measurementsSOD-like activity of Mn(II) beta-octabromo-meso-tetrakis(N-methylpyridinium-3-yl)porphyrin equals that of the enzyme itselfPharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP(5+), in plasma and major organs of B6C3F1 miceImpact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier.Manganoporphyrins increase ascorbate-induced cytotoxicity by enhancing H2O2 generationLipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways.Dinitrosyliron complexes and the mechanism(s) of cellular protein nitrosothiol formation from nitric oxideSalen Mn complexes mitigate radiation injury in normal tissues.Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.Compartmentalized oxidative stress in dopaminergic cell death induced by pesticides and complex I inhibitors: distinct roles of superoxide anion and superoxide dismutases.Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle.Antioxidant therapeutics: Pandora's box.Simple biological systems for assessing the activity of superoxide dismutase mimics.Manganese superoxide dismutase, MnSOD and its mimicsDesign, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.Bz-423 superoxide signals apoptosis via selective activation of JNK, Bak, and BaxOrally available Mn porphyrins with superoxide dismutase and catalase activities.Synthesis and characterization of bismuth(III) and antimony(V) porphyrins: high antileishmanial activity against antimony-resistant parasite.Quality of potent Mn porphyrin-based SOD mimics and peroxynitrite scavengers for pre-clinical mechanistic/therapeutic purposes.A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics.Determination of residual manganese in Mn porphyrin-based superoxide dismutase (SOD) and peroxynitrite reductase mimics.Thermal stability of the prototypical Mn porphyrin-based superoxide dismutase mimic and potent oxidative-stress redox modulator Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin chloride, MnTE-2-PyP(5+).Electrochemical Behavior and Voltammetric Determination of a Manganese(II) Complex at a Carbon Paste Electrode.Redox modulation of oxidative stress by Mn porphyrin-based therapeutics: the effect of charge distribution.A porphyrin-based fluorescence method for zinc determination in commercial propolis extracts without sample pretreatment.In situ redox reactions facilitate the assembly of a mixed-valence metal-organic nanocapsule.
P2860
Q28382968-698267D1-E119-40BD-A294-1497E0E0E2C5Q28385000-04C0265D-0ED0-4408-9026-24D3A0E9AF06Q28389277-742A8886-C4D0-4131-8086-A841F64B991CQ34021782-A97800B4-AE9A-42AB-BE30-BBF0683C68A0Q34110107-B4A5CDE4-7393-4D47-AF97-BA93F4CAF7F9Q34455737-000AB938-708D-44E1-AE7B-CBDDE37D203DQ34500616-52FF2D0D-EA79-40A8-B265-70666C9323C3Q35177269-99D3F3A3-AE66-4887-9F5D-656F979A7A70Q35228718-7F323133-E552-432C-B103-0B95BD282FCBQ35349280-468535D0-793D-4EF0-A56E-8EAAEEE91FC6Q36034130-33B38BAB-6D7E-4A60-8F69-CD89ED3C2503Q36961432-BE543831-12A5-4180-B8CC-334FFB5A03EBQ36973998-BAA3D513-5B4A-4FA1-A0E2-78ACE06FF8B5Q37038133-B4E87B14-EF70-4968-9AC5-A289E2327409Q37100095-68710C98-E02F-4036-9ACB-05E28408BC01Q37131042-21DA5D6C-B92E-4024-B2DF-729A47735C2DQ37140075-68338EA0-595F-44ED-97FE-1BF691BEBF7FQ37270688-8562AAA2-6F79-4EA1-9AA4-E4BE4E198FE8Q37342759-3E0F256C-BA78-48B8-97B6-0484E29B8237Q37445587-176F7FA0-1AF1-4383-8AC6-CC6224E65CB7Q37509229-84C1E63B-2E2E-4759-A96F-4D0B4FC962B3Q37576892-A67B9A00-7A58-425B-B9BA-BBF57024FBB7Q37734019-5CAA4AF2-F68F-4B6E-BA4F-3F205EAD2439Q37971277-2F9D0CBE-6FFB-481F-92C6-29671FC5DA24Q38053032-85F55647-31F5-4422-97D5-13A7D37478BFQ39579957-4EFBE7D9-2EDE-493E-ACED-EC17BBE39649Q39841516-12268115-FA43-427F-A7F1-31501EC2B232Q40991561-37E8ED4B-957A-495E-B07B-589ABD04FAEDQ41642173-A751FBB9-BED1-4A14-97B5-74408232F40CQ41812704-4074C2AC-ECEB-484A-B1B1-9E7D5B0C8E2FQ42567315-BA3F4F7D-A918-4F8F-BBF2-6D0DB6BC7EADQ43042063-5F34CB66-DF0C-44DF-A32B-1C33376DFCCAQ43081267-103F42F7-07E6-4115-9766-10485B1B952AQ46746480-E88BE083-7A60-4C79-A2C3-964548F3E9BDQ48133975-FF066409-E4E8-48E7-9264-DA7105EA13D9Q55200802-7DE7B50A-CB15-4425-BF2A-FCF5365EDC46
P2860
Pure manganese(III) 5,10,15,20-tetrakis(4-benzoic acid)porphyrin (MnTBAP) is not a superoxide dismutase mimic in aqueous systems: a case of structure-activity relationship as a watchdog mechanism in experimental therapeutics and biology.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Pure manganese(III) 5,10,15,20 ...... ntal therapeutics and biology.
@en
Pure manganese(III) 5,10,15,20 ...... ntal therapeutics and biology.
@nl
type
label
Pure manganese(III) 5,10,15,20 ...... ntal therapeutics and biology.
@en
Pure manganese(III) 5,10,15,20 ...... ntal therapeutics and biology.
@nl
prefLabel
Pure manganese(III) 5,10,15,20 ...... ntal therapeutics and biology.
@en
Pure manganese(III) 5,10,15,20 ...... ntal therapeutics and biology.
@nl
P2093
P1476
Pure manganese(III) 5,10,15,20 ...... ntal therapeutics and biology.
@en
P2093
Ines Batinić-Haberle
Ivan Spasojević
Júlio S Rebouças
P2888
P304
P356
10.1007/S00775-007-0324-9
P577
2007-11-29T00:00:00Z