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(-)-Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerasesIsolation of cDNA clones encoding the beta isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24Dietary polyphenols as topoisomerase II poisons: B ring and C ring substituents determine the mechanism of enzyme-mediated DNA cleavage enhancementMms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase IIImmunodetection of human topoisomerase I-DNA covalent complexesA domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase functionA naturally chimeric type IIA topoisomerase in Aquifex aeolicus highlights an evolutionary path for the emergence of functional paralogsCharacterization of DNA topoisomerase I from Candida albicans as a target for drug discoveryInhibition of human immunodeficiency virus integrase by bis-catecholsSelective inhibition of topoisomerases from Pneumocystis carinii compared with that of topoisomerases from mammalian cellsNumerical analysis of etoposide induced DNA breaksRole of minor groove width and hydration pattern on amsacrine interaction with DNANitric Oxide Down-Regulates Topoisomerase I and Induces Camptothecin Resistance in Human Breast MCF-7 Tumor CellsThe p14ARF alternate reading frame protein enhances DNA binding of topoisomerase I by interacting with the serine 506-phosphorylated core domain.Idarubicinol myelotoxicity: a comparison of in vitro data with clinical outcome in patients treated with high-dose idarubicin.Topoisomerase IIbeta activates a subset of neuronal genes that are repressed in AT-rich genomic environment.Fluoroquinolone-gyrase-DNA complexes: two modes of drug binding.Trovafloxacin enhances lipopolysaccharide-stimulated production of tumor necrosis factor-α by macrophages: role of the DNA damage response.Assessing sensitivity to antibacterial topoisomerase II inhibitors.Inhibition of calf thymus type II DNA topoisomerase by poly(ADP-ribosylation)In vivo topoisomerase II cleavage of the Drosophila histone and satellite III repeats: DNA sequence and structural characteristicsMutation of cysteine residue 455 to alanine in human topoisomerase IIalpha confers hypersensitivity to quinones: enhancing DNA scission by closing the N-terminal protein gate.Cleavage of plasmid DNA by eukaryotic topoisomerase II.Quinone-induced enhancement of DNA cleavage by human topoisomerase IIalpha: adduction of cysteine residues 392 and 405.The use of divalent metal ions by type II topoisomerases.Doxazolidine induction of apoptosis by a topoisomerase II independent mechanism.CK2-mediated hyperphosphorylation of topoisomerase I targets serine 506, enhances topoisomerase I-DNA binding, and increases cellular camptothecin sensitivity.Acidic pH induces topoisomerase II-mediated DNA damage.Recognition and repair of chemically heterogeneous structures at DNA endsThe recognition of DNA cleavage sites by porcine spleen topoisomerase IIKinetoplast-associated DNA topoisomerase in Crithidia fasciculata: crosslinking of mitochondrial topoisomerase II to both minicircles and maxicircles in cells treated with the topoisomerase inhibitor VP16Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress.Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα.In vitro cleavable-complex assay to monitor antimicrobial potency of quinolones.Use of in vitro topoisomerase II assays for studying quinolone antibacterial agentsUse of double-stranded DNA mini-circles to characterize the covalent topoisomerase-DNA complex.Sequence requirements for mammalian topoisomerase II mediated DNA cleavage stimulated by an ellipticine derivative.Local base sequence preferences for DNA cleavage by mammalian topoisomerase II in the presence of amsacrine or teniposide.Local sequence requirements for DNA cleavage by mammalian topoisomerase II in the presence of doxorubicin.A pyrimido[1,6-a]benzimidazole that enhances DNA cleavage mediated by eukaryotic topoisomerase II: a novel class of topoisomerase II-targeted drugs with cytotoxic potential
P2860
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P2860
description
1983 nî lūn-bûn
@nan
1983年の論文
@ja
1983年学术文章
@wuu
1983年学术文章
@zh
1983年学术文章
@zh-cn
1983年学术文章
@zh-hans
1983年学术文章
@zh-my
1983年学术文章
@zh-sg
1983年學術文章
@yue
1983年學術文章
@zh-hant
name
Cleavage of DNA by mammalian DNA topoisomerase II.
@en
Cleavage of DNA by mammalian DNA topoisomerase II.
@nl
type
label
Cleavage of DNA by mammalian DNA topoisomerase II.
@en
Cleavage of DNA by mammalian DNA topoisomerase II.
@nl
prefLabel
Cleavage of DNA by mammalian DNA topoisomerase II.
@en
Cleavage of DNA by mammalian DNA topoisomerase II.
@nl
P2093
P1476
Cleavage of DNA by mammalian DNA topoisomerase II.
@en
P2093
P304
15365-15370
P407
P577
1983-12-01T00:00:00Z