Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis
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Update in lung cancer 2007Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonismRepulsive axon guidance molecule Slit3 is a novel angiogenic factorPathophysiology of heparan sulphate: many diseases, few drugsHuman genetic disorders and knockout mice deficient in glycosaminoglycanExtracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning.Altered heparan sulfate structure in mice with deleted NDST3 gene function.Fell-Muir Lecture: Heparan sulphate and the art of cell regulation: a polymer chain conducts the protein orchestra.Heparan sulfate is required for embryonic stem cells to exit from self-renewalOvarian cancer cell heparan sulfate 6-O-sulfotransferases regulate an angiogenic program induced by heparin-binding epidermal growth factor (EGF)-like growth factor/EGF receptor signalingExtracellular matrix, inflammation, and the angiogenic response.Endothelial and leukocyte heparan sulfates regulate the development of allergen-induced airway remodeling in a mouse modelDeficiency of endothelial heparan sulfates attenuates allergic airway inflammation.Characterization of glycosaminoglycans by 15N NMR spectroscopy and in vivo isotopic labeling.Heparan sulfate Ndst1 regulates vascular smooth muscle cell proliferation, vessel size and vascular remodeling.Glycosaminoglycan binding facilitates entry of a bacterial pathogen into central nervous systemsHeparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.Lymphatic endothelial heparan sulfate deficiency results in altered growth responses to vascular endothelial growth factor-C (VEGF-C)The dominating role of N-deacetylase/N-sulfotransferase 1 in forming domain structures in heparan sulfateHeparan sulfate proteoglycans.Heparan sulfate expression in the neural crest is essential for mouse cardiogenesis.The involvement of proteoglycans in the human plasma prekallikrein interaction with the cell surface.High-resolution probing heparan sulfate-antithrombin interaction on a single endothelial cell surface: single-molecule AFM studies.A Heparan Sulfate-Binding Cell Penetrating Peptide for Tumor Targeting and Migration Inhibition.Heparan sulfate is essential for high mobility group protein 1 (HMGB1) signaling by the receptor for advanced glycation end products (RAGE).Functional overlap between chondroitin and heparan sulfate proteoglycans during VEGF-induced sprouting angiogenesis.Role of Deacetylase Activity of N-Deacetylase/N-Sulfotransferase 1 in Forming N-Sulfated Domain in Heparan SulfateThe glomerular basement membrane as a model system to study the bioactivity of heparan sulfate glycosaminoglycans.Heparan sulfate and syndecan-1 are essential in maintaining murine and human intestinal epithelial barrier functionGlypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells.Endothelial heparan sulfate 6-O-sulfation levels regulate angiogenic responses of endothelial cells to fibroblast growth factor 2 and vascular endothelial growth factor.The role of the VEGF-C/VEGFRs axis in tumor progression and therapy.Proteoglycans and their roles in brain cancer.Multivalent proteoglycan modulation of FGF mitogenic responses in perivascular cells.Surfen, a small molecule antagonist of heparan sulfateEndothelial heparan sulfate in angiogenesis.Syndecan-1: a dynamic regulator of the myeloma microenvironment.Glycan antagonists and inhibitors: a fount for drug discovery.Functional Importance of a Proteoglycan Coreceptor in Pathologic LymphangiogenesisHeparan sulphate biosynthesis and disease.
P2860
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P2860
Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis
@ast
Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis
@en
type
label
Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis
@ast
Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis
@en
prefLabel
Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis
@ast
Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis
@en
P2093
P2860
P356
P1476
Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis
@en
P2093
Janice Castagnola
Jeffrey D Esko
Joseph R Bishop
Katherine A Radek
Krisanavane Reddi
Lianchun Wang
Lyudmila Sikora
Manuela Schuksz
Mark M Fuster
P Sriramarao
P2860
P304
P356
10.1083/JCB.200610086
P407
P577
2007-04-30T00:00:00Z