Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes. - sprookjes - yvandenbroek - TriplyDB

Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes.

Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes.

http://www.wikidata.org/entity/Q38409513

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Tumor suppressor protein VHL inhibits Hedgehog-Gli activation through suppression of Gli1 nuclear localization GLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cells Non-Canonical Hh Signaling in Cancer-Current Understanding and Future Directions The Role of Hedgehog Signaling in Tumor Induced Bone Disease Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy Basal cell carcinoma - molecular biology and potential new therapies Hedgehog signaling pathway and its targets for treatment in basal cell carcinoma Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy SOX9 inhibits β-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.Hedgehog signaling and the Gli code in stem cells, cancer, and metastases FGF receptors: cancer biology and therapeutics Computational prediction and experimental verification of new MAP kinase docking sites and substrates including Gli transcription factors Structural and logical analysis of a comprehensive hedgehog signaling pathway to identify alternative drug targets for glioma, colon and pancreatic cancer Induction of specific microRNAs inhibits cutaneous wound healing Cx43 mediates TGF-beta signaling through competitive Smads binding to microtubules.Non-consensus GLI binding sites in Hedgehog target gene regulation.Role of FGFR2-signaling in the pathogenesis of acne.cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells.GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent state Targeting Hedgehog--a cancer stem cell pathway Sonic hedgehog-Gli1 signaling pathway regulates the epithelial mesenchymal transition (EMT) by mediating a new target gene, S100A4, in pancreatic cancer cells Recent advances on skin-resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti-aging and cancer therapies.Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway.Gli as a novel therapeutic target in malignant pleural mesothelioma The Gli code: an information nexus regulating cell fate, stemness and cancer.Glioma-associated oncogene family zinc finger 1 expression and metastasis in patients with head and neck squamous cell carcinoma treated with radiation therapy (RTOG 9003)Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis Hedgehog/GLI signaling activates suppressor of cytokine signaling 1 (SOCS1) in epidermal and neural tumor cells Regulation of sonic hedgehog expression by integrin β1 and epidermal growth factor receptor in intestinal epithelium Hedgehog/GLI and PI3K signaling in the initiation and maintenance of chronic lymphocytic leukemia.Basal cell carcinomas: attack of the hedgehog.Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.Cooperative Hedgehog-EGFR signaling Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells Blockade of Hedgehog Signaling Synergistically Increases Sensitivity to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Cancer Cell Lines Interleukin-1 Receptor Type 2 Acts with c-Fos to Enhance the Expression of Interleukin-6 and Vascular Endothelial Growth Factor A in Colon Cancer Cells and Induce Angiogenesis.Impact of Sonic Hedgehog Pathway Expression on Outcome in HPV Negative Head and Neck Carcinoma Patients after Surgery and Adjuvant Radiotherapy Olfactomedin 4 deficiency promotes prostate neoplastic progression and is associated with upregulation of the hedgehog-signaling pathway.A model of spatially restricted transcription in opposing gradients of activators and repressors

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Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes.

http://www.wikidata.org/entity/Q38409513

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

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name

Selective modulation of Hedgeh ...... naling in human keratinocytes.

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type

label

Selective modulation of Hedgeh ...... naling in human keratinocytes.

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Selective modulation of Hedgeh ...... naling in human keratinocytes.

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Molecular and Cellular Biology

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Selective modulation of Hedgeh ...... gnaling in human keratinocytes

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P2093

Carmen Schmid

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Cornelia Hauser-Kronberger

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Gerhard Regl

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Graham W Neill

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Harald Schnidar

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Michael P Philpott

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Michaela Hanneder

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Stefan Klingler

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P2860

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

GLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localization

Gli1 protein is expressed in basal cell carcinomas, outer root sheath keratinocytes and a subpopulation of mesenchymal cells in normal human skin

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter

Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma

A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2

Cloning of novel isoforms of the human Gli2 oncogene and their activities to enhance tax-dependent transcription of the human T-cell leukemia virus type 1 genome

Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4

A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

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6283-6298

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scholarly article

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10.1128/MCB.02317-05

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16

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26

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2006-08-01T00:00:00Z

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6905228

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16880536

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1592816

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