A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA
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Transforming growth factor beta -inducible independent binding of SMAD to the Smad7 promoterPromoting bone morphogenetic protein signaling through negative regulation of inhibitory SmadsSmad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formationSmad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesionJab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradationIdentification of PCTA, a TGIF antagonist that promotes PML function in TGF-beta signallingTransforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradationGADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptorThe functional genomic response of developing embryonic submandibular glands to NF-kappa B inhibitionGlobal gene expression in neuroendocrine tumors from patients with the MEN1 syndromeCytokine and anti-cytokine therapies in prevention or treatment of fibrosis in IBDExperimental evidence of ω-3 polyunsaturated fatty acid modulation of inflammatory cytokines and bioactive lipid mediators: their potential role in inflammatory, neurodegenerative, and neoplastic diseasesTumor necrosis factor α inhibits expression of the iron regulating hormone hepcidin in murine models of innate colitisIKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel diseaseNuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activityTGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signalingThrombospondin 1 acts as a strong promoter of transforming growth factor beta effects via two distinct mechanisms in hepatic stellate cellsEcsit is required for Bmp signaling and mesoderm formation during mouse embryogenesisThe p65 subunit of NF-κB inhibits COL1A1 gene transcription in human dermal and scleroderma fibroblasts through its recruitment on promoter by protein interaction with transcriptional activators (c-Krox, Sp1, and Sp3).Cytomegalovirus induces abnormal chondrogenesis and osteogenesis during embryonic mandibular development.Early administration of probiotic Lactobacillus acidophilus and/or prebiotic inulin attenuates pathogen-mediated intestinal inflammation and Smad 7 cell signaling.Tumor-fibroblast interactions stimulate tumor vascularization by enhancing cytokine-driven production of MMP9 by tumor cells.IL1B induced Smad 7 negatively regulates gastrin expression.Conditional epidermal expression of TGFbeta 1 blocks neonatal lethality but causes a reversible hyperplasia and alopeciaInvasive candidiasis stimulates hepatocyte and monocyte production of active transforming growth factor beta.Smad3 knock-out mice as a useful model to study intestinal fibrogenesisDeficient Smad7 expression: a putative molecular defect in scleroderma.TRAF6 mediates IL-1β/LPS-induced suppression of TGF-β signaling through its interaction with the type III TGF-β receptor.Smad7 inhibits autocrine expression of TGF-β2 in intestinal epithelial cells in baboon necrotizing enterocolitisTGFβ loss activates ADAMTS-1-mediated EGF-dependent invasion in a model of esophageal cell invasion.Renal interstitial fibrosis induced by high-dose mesoporous silica nanoparticles via the NF-κB signaling pathway.Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networksIdentification of genes responsible for osteoblast differentiation from human mesodermal progenitor cells.Renal gene and protein expression signatures for prediction of kidney disease progressionExpression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkaliMyofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1Molecular mechanisms and in vivo mouse models of skin aging associated with dermal matrix alterations.TAK1-TAB2 signaling contributes to bone destruction by breast carcinoma cells
P2860
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P2860
A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA
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2000 nî lūn-bûn
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2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2000 թվականի հունվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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name
A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA
@ast
A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA
@en
A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA
@nl
type
label
A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA
@ast
A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA
@en
A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA
@nl
prefLabel
A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA
@ast
A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA
@en
A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA
@nl
P2093
P2860
P1433
P1476
A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA
@en
P2093
A Dominguez-Rosales
E P Böttinger
G von Gersdorff
P2860
P304
P407
P577
2000-01-01T00:00:00Z