Current understanding of LRRK2 in Parkinson's disease: biochemical and structural features and inhibitor design
about
The Parkinson disease-linked LRRK2 protein mutation I2020T stabilizes an active state conformation leading to increased kinase activityLRRK2 inhibitors and their potential in the treatment of Parkinson's disease: current perspectivesUnique functional and structural properties of the LRRK2 protein ATP-binding pocket.Topological Fingerprints as an Aid in Finding Structural Patterns for LRRK2 Inhibition.LRRK2: an éminence grise of Wnt-mediated neurogenesis?Altered Development of Synapse Structure and Function in Striatum Caused by Parkinson's Disease-Linked LRRK2-G2019S MutationStructure, function, and leucine-rich repeat kinase 2: On the importance of reproducibility in understanding Parkinson's disease.A triazole derivative elicits autophagic clearance of polyglutamine aggregation in neuronal cells.LRRK2, a puzzling protein: insights into Parkinson's disease pathogenesisCellular processes associated with LRRK2 function and dysfunctionForeword: neurodegenerative diseases: challenges and opportunities.Current therapeutic molecules and targets in neurodegenerative diseases based on in silico drug design.
P2860
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P2860
Current understanding of LRRK2 in Parkinson's disease: biochemical and structural features and inhibitor design
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Current understanding of LRRK2 ...... features and inhibitor design
@ast
Current understanding of LRRK2 ...... features and inhibitor design
@en
Current understanding of LRRK2 ...... features and inhibitor design
@nl
type
label
Current understanding of LRRK2 ...... features and inhibitor design
@ast
Current understanding of LRRK2 ...... features and inhibitor design
@en
Current understanding of LRRK2 ...... features and inhibitor design
@nl
prefLabel
Current understanding of LRRK2 ...... features and inhibitor design
@ast
Current understanding of LRRK2 ...... features and inhibitor design
@en
Current understanding of LRRK2 ...... features and inhibitor design
@nl
P2860
P3181
P356
P1476
Current understanding of LRRK2 ...... features and inhibitor design
@en
P2093
P2860
P304
P3181
P356
10.4155/FMC.12.110
P407
P577
2012-09-01T00:00:00Z