Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination
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Monosomy 18pHistogenesis of retinal dysplasia in trisomy 13A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBPEpithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusionIdentification of PCTA, a TGIF antagonist that promotes PML function in TGF-beta signallingRegulation of TG-interacting factor by transforming growth factor-betaOverlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development.Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF.Transforming growth interacting factor expression in leiomyoma compared with myometriumTgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation.Functional analysis of mutations in TGIF associated with holoprosencephaly.The Syndrome of Frontonasal Dysplasia, Callosal Agenesis, Basal Encephalocele, and Eye Anomalies - Phenotypic and Aetiological ConsiderationsDcode.org anthology of comparative genomic toolsThe Tgif2 gene contains a retained intron within the coding sequence.TALE transcription factors during early development of the vertebrate brain and eyeThe interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIFTGIF2 interacts with histone deacetylase 1 and represses transcriptionMolecular diagnosis of a novel heterozygous 268C-->T (R90C) mutation in TGIF gene in a fetus with holoprosencephaly and premaxillary agenesisIntraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brainEmbryonic fibroblasts from mice lacking Tgif were defective in cell cyclingPremature senescence and increased TGFβ signaling in the absence of Tgif1.Mammalian twisted gastrulation is essential for skeleto-lymphogenesisTGIF inhibits retinoid signalingWidespread macromolecular interaction perturbations in human genetic disordersTgif1 and Tgif2 Repress Expression of the RabGAP Evi5l.Genetic and Molecular Analyses indicate independent effects of TGIFs on Nodal and Gli3 in neural tube patterning.Tgif1 and Tgif2 Regulate Axial Patterning in Mouse.Zebrafish in Brazilian Science: Scientific Production, Impact, and Collaboration.TG-interacting factor 1 acts as a transcriptional repressor of sterol O-acyltransferase 2.Tgif1 regulates quiescence and self-renewal of hematopoietic stem cellsLoss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.Tgif1 represses apolipoprotein gene expression in liver.Drosophila TGIF proteins are transcriptional activators.Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease.Holoprosencephaly.Single median maxillary central incisor: new data and mutation review.Dissecting the genetics of human high myopia: a molecular biologic approachCurrent recommendations for the molecular evaluation of newly diagnosed holoprosencephaly patientsThe molecular genetics of holoprosencephaly.Holoprosencephaly and agnathia spectrum: Presentation of two new patients and review of the literature.
P2860
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P2860
Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination
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2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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Mutations in TGIF cause holopr ...... uman neural axis determination
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Mutations in TGIF cause holopr ...... uman neural axis determination
@en
Mutations in TGIF cause holopr ...... uman neural axis determination
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Mutations in TGIF cause holopr ...... uman neural axis determination
@ast
Mutations in TGIF cause holopr ...... uman neural axis determination
@en
Mutations in TGIF cause holopr ...... uman neural axis determination
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Mutations in TGIF cause holopr ...... uman neural axis determination
@ast
Mutations in TGIF cause holopr ...... uman neural axis determination
@en
Mutations in TGIF cause holopr ...... uman neural axis determination
@nl
P2093
P50
P3181
P356
P1433
P1476
Mutations in TGIF cause holopr ...... uman neural axis determination
@en
P2093
A Richieri-Costa
E H Zackai
E Roessler
M C Edwards
P Meinecke
S J Elledge
P2888
P304
P3181
P356
10.1038/76074
P407
P577
2000-06-01T00:00:00Z