Greatly reduced efficiency of both positive and negative selection of thymocytes in CD45 tyrosine phosphatase-deficient mice
about
The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cellsAuxiliary splice factor U2AF26 and transcription factor Gfi1 cooperate directly in regulating CD45 alternative splicingDevelopment of T-leukaemias in CD45 tyrosine phosphatase-deficient mutant lck miceNovel tools to dissect the dynamic regulation of TCR signaling by the kinase Csk and the phosphatase CD45CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic developmentIntra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis.CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cellsGenome-wide mouse mutagenesis reveals CD45-mediated T cell function as critical in protective immunity to HSV-1.Viral interference with functions of the cellular receptor tyrosine phosphatase CD45.Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival.CD45 Isoform Profile Identifies Natural Killer (NK) Subsets with Differential Activity.The Mouse Cytomegalovirus Gene m42 Targets Surface Expression of the Protein Tyrosine Phosphatase CD45 in Infected Macrophages.An extracatalytic function of CD45 in B cells is mediated by CD22.A requirement for CD45 distinguishes Ly49D-mediated cytokine and chemokine production from killing in primary natural killer cells.The structural wedge domain of the receptor-like tyrosine phosphatase CD45 enforces B cell tolerance by regulating substrate specificity.Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases.Selective regulation of TCR signaling pathways by the CD45 protein tyrosine phosphatase during thymocyte development.CD45 glycosylation controls T-cell life and death.PTPN22 deficiency cooperates with the CD45 E613R allele to break tolerance on a non-autoimmune background.Regulation of TCR signalling by tyrosine phosphatases: from immune homeostasis to autoimmunity.Receptor-like tyrosine phosphatases CD45 and CD148 have distinct functions in chemoattractant-mediated neutrophil migration and response to S. aureus.Identification of Anti-tumor Cells Carrying Natural Killer (NK) Cell Antigens in Patients With Hematological Cancers.Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling.CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers.The role of intron sequences in high level expression from CD45 cDNA constructs.CD45 regulates GM-CSF, retinoic acid and T-cell homing in intestinal inflammation.
P2860
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P2860
Greatly reduced efficiency of both positive and negative selection of thymocytes in CD45 tyrosine phosphatase-deficient mice
description
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1999
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im September 1999 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 1999/09/01)
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vědecký článek publikovaný v roce 1999
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wetenschappelijk artikel (gepubliceerd op 1999/09/01)
@nl
наукова стаття, опублікована у вересні 1999
@uk
مقالة علمية (نشرت في سبتمبر 1999)
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name
Greatly reduced efficiency of ...... ine phosphatase-deficient mice
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Greatly reduced efficiency of ...... ine phosphatase-deficient mice
@en
Greatly reduced efficiency of ...... ine phosphatase-deficient mice
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type
label
Greatly reduced efficiency of ...... ine phosphatase-deficient mice
@ast
Greatly reduced efficiency of ...... ine phosphatase-deficient mice
@en
Greatly reduced efficiency of ...... ine phosphatase-deficient mice
@nl
prefLabel
Greatly reduced efficiency of ...... ine phosphatase-deficient mice
@ast
Greatly reduced efficiency of ...... ine phosphatase-deficient mice
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Greatly reduced efficiency of ...... ine phosphatase-deficient mice
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P2093
P3181
P356
P1476
Greatly reduced efficiency of ...... ine phosphatase-deficient mice
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P2093
M. A. Basson
P. S. Costello
V. L. Tybulewicz
P2860
P304
P3181
P356
10.1002/(SICI)1521-4141(199909)29:09<2923::AID-IMMU2923>3.0.CO;2-Y
10.1002/(SICI)1521-4141(199909)29:09<2923::AID-IMMU2923>3.3.CO;2-P
P407
P577
1999-09-01T00:00:00Z