Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma. - Wikidata - awgldk - TriplyDB

Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma.

Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma.

http://www.wikidata.org/entity/Q30494625

about

Evolutionarily divergent, unstable filamentous actin is essential for gliding motility in apicomplexan parasites Recent insights into apicomplexan parasite egress provide new views to a kill Chemical biology approaches for the study of apicomplexan parasites The calcium signaling toolkit of the Apicomplexan parasites Toxoplasma gondii and Plasmodium spp Parasite Calcineurin Regulates Host Cell Recognition and Attachment by Apicomplexans Pyrimidinergic Receptor Activation Controls Toxoplasma gondii Infection in Macrophages Reduced parasite motility and micronemal protein secretion by a p38 MAPK inhibitor leads to a severe impairment of cell invasion by the apicomplexan parasite Eimeria tenella TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells The motility of a human parasite, Toxoplasma gondii, is regulated by a novel lysine methyltransferase Chemical genetic strategy for targeting protein kinases based on covalent complementarity Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1 Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia Potent and Selective Inhibitors of CDPK1 from T. gondii and C. parvum Based on a 5-Aminopyrazole-4-carboxamide Scaffold Neospora caninum calcium-dependent protein kinase 1 is an effective drug target for neosporosis therapy A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes Global analysis of apicomplexan protein S-acyl transferases reveals an enzyme essential for invasion Role of calcineurin and actin dynamics in regulated secretion of microneme proteins in Plasmodium falciparum merozoites during erythrocyte invasion A forward genetic screen reveals that calcium-dependent protein kinase 3 regulates egress in Toxoplasma Forward genetic screening identifies a small molecule that blocks Toxoplasma gondii growth by inhibiting both host- and parasite-encoded kinases Phosphorylation of a Myosin Motor by TgCDPK3 Facilitates Rapid Initiation of Motility during Toxoplasma gondii egress Phosphatidylthreonine and Lipid-Mediated Control of Parasite Virulence Identification and Validation of Small-Gatekeeper Kinases as Drug Targets in Giardia lamblia A DOC2 protein identified by mutational profiling is essential for apicomplexan parasite exocytosis Actin depolymerizing factor controls actin turnover and gliding motility in Toxoplasma gondii Distinct signalling pathways control Toxoplasma egress and host-cell invasion Calcium-dependent phosphorylation alters class XIVa myosin function in the protozoan parasite Toxoplasma gondii Serum Albumin Stimulates Protein Kinase G-dependent Microneme Secretion in Toxoplasma gondii Plasma Membrane Association by N-Acylation Governs PKG Function in Toxoplasma gondii Multiple short windows of calcium-dependent protein kinase 4 activity coordinate distinct cell cycle events during Plasmodium gametogenesis.Bumped kinase inhibitor 1294 treats established Toxoplasma gondii infection.PfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum.The Toxoplasma gondii calcium-dependent protein kinase 7 is involved in early steps of parasite division and is crucial for parasite survival.Evaluation of immune responses in mice after DNA immunization with putative Toxoplasma gondii calcium-dependent protein kinase 5.Quantitative in vivo analyses reveal calcium-dependent phosphorylation sites and identifies a novel component of the Toxoplasma invasion motor complex Structural and evolutionary divergence of eukaryotic protein kinases in Apicomplexa.How apicomplexan parasites move in and out of cells.Protective efficacy of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) adjuvated with recombinant IL-15 and IL-21 against experimental toxoplasmosis in mice Dual transcriptional profiling of mice and Toxoplasma gondii during acute and chronic infection Mechanisms of microbial escape from phagocyte killing.Diversity of extracellular proteins during the transition from the 'proto-apicomplexan' alveolates to the apicomplexan obligate parasites.

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Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma.

http://www.wikidata.org/entity/Q30494625

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2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma.

@ast

Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma.

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type

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Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma.

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Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma.

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Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma.

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Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma.

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Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma.

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Chao Zhang

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Joel Shuman

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Kevan M Shokat

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Raymond Hui

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Sebastian Lourido

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P2860

Structure-guided development of affinity probes for tyrosine kinases using chemical genetics

Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium

Role of Toxoplasma gondii myosin A in powering parasite gliding and host cell invasion

A chemical switch for inhibitor-sensitive alleles of any protein kinase

Time-lapse video microscopy of gliding motility in Toxoplasma gondii reveals a novel, biphasic mechanism of cell locomotion.

Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells.

Dysferlin and the plasma membrane repair in muscular dystrophy.

CaM kinase II: a protein kinase with extraordinary talents germane to insulin exocytosis.

Use of the kinase inhibitor analog 1NM-PP1 reveals a role for Toxoplasma gondii CDPK1 in the invasion step.

Molecular genetics of regulated secretion in paramecium.

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465

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