Oleamide: an endogenous sleep-inducing lipid and prototypical member of a new class of biological signaling molecules.
about
The endocannabinoid system as an emerging target of pharmacotherapyBinding and Inactivation Mechanism of a Humanized Fatty Acid Amide Hydrolase by α-Ketoheterocycle Inhibitors Revealed from Cocrystal StructuresX-ray Crystallographic Analysis of α-Ketoheterocycle Inhibitors Bound to a Humanized Variant of Fatty Acid Amide HydrolaseFluoride-Mediated Capture of a Noncovalent Bound State of a Reversible Covalent Enzyme Inhibitor: X-ray Crystallographic Analysis of an Exceptionally Potent α-Ketoheterocycle Inhibitor of Fatty Acid Amide HydrolaseReversible Competitive α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Constraints in the Acyl Side Chain: Orally Active, Long-Acting AnalgesicsRational Design of Fatty Acid Amide Hydrolase Inhibitors That Act by Covalently Bonding to Two Active Site ResiduesFunctional role of gap junctions in cytokine-induced leukocyte adhesion to endothelium in vivo.The developmental decrease in REM sleep: the role of transmitters and electrical coupling.TRANSLATION OF BRAIN ACTIVITY INTO SLEEP.α-Ketoheterocycle inhibitors of fatty acid amide hydrolase: exploration of conformational constraints in the acyl side chain.Cytokines in immune function and sleep regulation.The discovery and development of inhibitors of fatty acid amide hydrolase (FAAH).Discovery libraries targeting the major enzyme classes: the serine hydrolases.Membrane protein crystallization in meso: lipid type-tailoring of the cubic phaseMicrowave Assisted Synthesis of Sodium Sulfonates Precursors of Sulfonyl Chlorides and Fluorides.The expanding field of cannabimimetic and related lipid mediators.Preventive effects of a fermented dairy product against Alzheimer's disease and identification of a novel oleamide with enhanced microglial phagocytosis and anti-inflammatory activityManipulation of the endocannabinoid system by a general anaestheticDifferential effects of single versus repeated alcohol withdrawal on the expression of endocannabinoid system-related genes in the rat amygdala.α-Ketoheterocycle-based Inhibitors of Fatty Acid Amide Hydrolase (FAAH).Discovery of a potent, selective, and efficacious class of reversible alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase effective as analgesicsDelineation of a fundamental alpha-ketoheterocycle substituent effect for use in the design of enzyme inhibitors.A Double Whammy: Targeting Both Fatty Acid Amide Hydrolase (FAAH) and Cyclooxygenase (COX) To Treat Pain and Inflammation.Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolaseStructure-activity relationships of alpha-ketooxazole inhibitors of fatty acid amide hydrolaseOptimization of the central heterocycle of alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase.Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamideExploration of a fundamental substituent effect of alpha-ketoheterocycle enzyme inhibitors: Potent and selective inhibitors of fatty acid amide hydrolase.Optimization of alpha-ketooxazole inhibitors of fatty acid amide hydrolase.Design, synthesis, and characterization of α-ketoheterocycles that additionally target the cytosolic port Cys269 of fatty acid amide hydrolaseFatty acid amide signaling molecules.A metabolic-transcriptional network links sleep and cellular energetics in the brain.Coherence and frequency in the reticular activating system (RAS).Aryl Piperazinyl Ureas as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) in Rat, Dog, and Primate.Oleamide is a selective endogenous agonist of rat and human CB1 cannabinoid receptors.In vivo evidence that N-oleoylglycine acts independently of its conversion to oleamide.The Difference a Single Atom Can Make: Synthesis and Design at the Chemistry-Biology Interface.
P2860
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P2860
Oleamide: an endogenous sleep-inducing lipid and prototypical member of a new class of biological signaling molecules.
description
1998 nî lūn-bûn
@nan
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Oleamide: an endogenous sleep- ...... iological signaling molecules.
@ast
Oleamide: an endogenous sleep- ...... iological signaling molecules.
@en
type
label
Oleamide: an endogenous sleep- ...... iological signaling molecules.
@ast
Oleamide: an endogenous sleep- ...... iological signaling molecules.
@en
prefLabel
Oleamide: an endogenous sleep- ...... iological signaling molecules.
@ast
Oleamide: an endogenous sleep- ...... iological signaling molecules.
@en
P2093
P1476
Oleamide: an endogenous sleep- ...... iological signaling molecules.
@en
P2093
Cravatt BF
Henriksen SJ
P304
P577
1998-08-01T00:00:00Z