Selection and characterization of beta-lactam-beta-lactamase inactivator-resistant mutants following PCR mutagenesis of the TEM-1 beta-lactamase gene
about
Three decades of beta-lactamase inhibitorsGenetic and Structural Characterization of an L201P Global Suppressor Substitution in TEM-1 β-LactamaseThe Importance of thetrans-Enamine Intermediate as a β-Lactamase Inhibition Strategy Probed in Inhibitor-Resistant SHV β-Lactamase VariantsNetwork models of TEM β-lactamase mutations coevolving under antibiotic selection show modular structure and anticipate evolutionary trajectoriesInsight into the effect of inhibitor resistant S130G mutant on physico-chemical properties of SHV type beta-lactamase: a molecular dynamics studyThe importance of a critical protonation state and the fate of the catalytic steps in class A beta-lactamases and penicillin-binding proteins.The role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276.Initial mutations direct alternative pathways of protein evolutionMolecular characterization of TEM-59 (IRT-17), a novel inhibitor-resistant TEM-derived beta-lactamase in a clinical isolate of Klebsiella oxytocaTEM-80, a novel inhibitor-resistant beta-lactamase in a clinical isolate of Enterobacter cloacaeCombining computational and experimental screening for rapid optimization of protein propertiesPFunkel: efficient, expansive, user-defined mutagenesis.Predicting evolutionary potential: in vitro evolution accurately reproduces natural evolution of the tem beta-lactamase.Experimental prediction of the natural evolution of antibiotic resistanceExperimental prediction of the evolution of cefepime resistance from the CMY-2 AmpC beta-lactamase.Cytoplasmic-membrane anchoring of a class A beta-lactamase and its capacity in manifesting antibiotic resistanceNovel Computational Protocols for Functionally Classifying and Characterising Serine Beta-Lactamases.Construction and characterization of mutants of the TEM-1 beta-lactamase containing amino acid substitutions associated with both extended-spectrum resistance and resistance to beta-lactamase inhibitors.Mutant TEM beta-lactamase producing resistance to ceftazidime, ampicillins, and beta-lactamase inhibitors.Beta-lactamases in ampicillin-resistant Escherichia coli isolates from foods, humans, and healthy animals.Mutations in the aph(2")-Ic gene are responsible for increased levels of aminoglycoside resistanceHaemophilus influenzae bla(ROB-1) mutations in hypermutagenic deltaampC Escherichia coli conferring resistance to cefotaxime and beta-lactamase inhibitors and increased susceptibility to cefaclor
P2860
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P2860
Selection and characterization of beta-lactam-beta-lactamase inactivator-resistant mutants following PCR mutagenesis of the TEM-1 beta-lactamase gene
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
Selection and characterization ...... the TEM-1 beta-lactamase gene
@ast
Selection and characterization ...... the TEM-1 beta-lactamase gene
@en
type
label
Selection and characterization ...... the TEM-1 beta-lactamase gene
@ast
Selection and characterization ...... the TEM-1 beta-lactamase gene
@en
prefLabel
Selection and characterization ...... the TEM-1 beta-lactamase gene
@ast
Selection and characterization ...... the TEM-1 beta-lactamase gene
@en
P2093
P2860
P1476
Selection and characterization ...... the TEM-1 beta-lactamase gene
@en
P2093
S A Lerner
S B Vakulenko
S Mobashery
P2860
P304
P407
P577
1998-07-01T00:00:00Z