The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia. - Wikidata - awgldk - TriplyDB

The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia.

The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia.

http://www.wikidata.org/entity/Q33808415

about

Unified theory of Alzheimer's disease (UTAD): implications for prevention and curative therapy Amyloidosis in Retinal Neurodegenerative Diseases Dementia of the eye: the role of amyloid beta in retinal degeneration Behavioral assays with mouse models of Alzheimer's disease: practical considerations and guidelines.Neuropathological alterations in Alzheimer disease Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's disease Structural evolution and membrane interactions of Alzheimer's amyloid-beta peptide oligomers: new knowledge from single-molecule fluorescence studies Alzheimer's disease--a panorama glimpse Early etiology of Alzheimer's disease: tipping the balance toward autophagy or endosomal dysfunction?Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier Amyloid-β and proinflammatory cytokines utilize a prion protein-dependent pathway to activate NADPH oxidase and induce cofilin-actin rods in hippocampal neurons Brain intraventricular injection of amyloid-β in zebrafish embryo impairs cognition and increases tau phosphorylation, effects reversed by lithium Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons.Novel antibody capture assay for paraffin-embedded tissue detects wide-ranging amyloid beta and paired helical filament-tau accumulation in cognitively normal older adults.Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation.The effect of PN-1, a Traditional Chinese Prescription, on the Learning and Memory in a Transgenic Mouse Model of Alzheimer's Disease.Brain amyloid-β oligomers in ageing and Alzheimer's disease.³H-deprenyl and ³H-PIB autoradiography show different laminar distributions of astroglia and fibrillar β-amyloid in Alzheimer brain Highly potent soluble amyloid-β seeds in human Alzheimer brain but not cerebrospinal fluid Recent Progress in Alzheimer's Disease Research, Part 3: Diagnosis and Treatment.The complexities underlying age-related macular degeneration: could amyloid beta play an important role?The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice Secreted amyloid β-proteins in a cell culture model include N-terminally extended peptides that impair synaptic plasticity Aβ oligomers inhibit synapse remodelling necessary for memory consolidation.RNA oxidation adducts 8-OHG and 8-OHA change with Aβ42 levels in late-stage Alzheimer's disease The intersection of amyloid beta and tau at synapses in Alzheimer's disease Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils.A critique of the drug discovery and phase 3 clinical programs targeting the amyloid hypothesis for Alzheimer disease.Human anti-Aβ IgGs target conformational epitopes on synthetic dimer assemblies and the AD brain-derived peptide.Isolation and characterization of antibody fragments selective for specific protein morphologies from nanogram antigen samples.Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation Macrocyclic β-sheet peptides that inhibit the aggregation of a tau-protein-derived hexapeptide.Disruption of amyloid plaques integrity affects the soluble oligomers content from Alzheimer disease brains.Synergistic interactions between Alzheimer's Aβ40 and Aβ42 on the surface of primary neurons revealed by single molecule microscopy.mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites A monoclonal antibody against synthetic Aβ dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting Aβ.AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56-kDa assembly Soluble Aβ seeds are potent inducers of cerebral β-amyloid deposition Amyloid-β-induced amyloid-β secretion: a possible feed-forward mechanism in Alzheimer's Disease.

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The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia.

http://www.wikidata.org/entity/Q33808415

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2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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The presence of sodium dodecyl ...... with Alzheimer-type dementia.

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The presence of sodium dodecyl ...... with Alzheimer-type dementia.

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The presence of sodium dodecyl ...... with Alzheimer-type dementia.

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The presence of sodium dodecyl ...... with Alzheimer-type dementia.

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The presence of sodium dodecyl ...... with Alzheimer-type dementia.

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The presence of sodium dodecyl ...... with Alzheimer-type dementia.

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The presence of sodium dodecyl ...... d with Alzheimer-type dementia

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P2093

Alfred T Welzel

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Dennis J Selkoe

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Dominic M Walsh

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Ganesh M Shankar

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Gill Forster

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Jessica M Mc Donald

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Medical Research Council Cognitive Function and Ageing Study

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P2860

beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

Neuropathological stageing of Alzheimer-related changes

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

Epidemiological pathology of dementia: attributable-risks at death in the Medical Research Council Cognitive Function and Ageing Study

Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques

Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment

Alzheimer's disease is a synaptic failure

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1328-1341

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scholarly article

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10.1093/BRAIN/AWQ065

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Pt 5

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133

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George M. Savva

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2010-04-19T00:00:00Z

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43201334

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20403962

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Alzheimer's disease

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2859152

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