Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosomal instability. - Wikidata - awgldk - TriplyDB

Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosomal instability.

Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosomal instability.

http://www.wikidata.org/entity/Q33963998

about

Inhibition of topoisomerase I prevents chromosome breakage at common fragile sites Molecular basis for expression of common and rare fragile sites The imprinted region on human chromosome 7q32 extends to the carboxypeptidase A gene cluster: an imprinted candidate for Silver-Russell syndrome Common fragile sites: genomic hotspots of DNA damage and carcinogenesis ReplicationDomain: a visualization tool and comparative database for genome-wide replication timing data Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites.Temporal differences in DNA replication during the S phase using single fiber analysis of normal human fibroblasts and glioblastoma T98G cells ATR preferentially interacts with common fragile site FRA3B and the binding requires its kinase activity in response to aphidicolin treatment.DNA breaks at fragile sites generate oncogenic RET/PTC rearrangements in human thyroid cells.Secondary structure formation and DNA instability at fragile site FRA16B Mechanisms of genomic instabilities underlying two common fragile-site-associated loci, PARK2 and DMD, in germ cell and cancer cell lines DNA instability at chromosomal fragile sites in cancer Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites.DNA topoisomerases participate in fragility of the oncogene RET.Coincidence of synteny breakpoints with malignancy-related deletions on human chromosome 3.Break-seq reveals hydroxyurea-induced chromosome fragility as a result of unscheduled conflict between DNA replication and transcription A deletion at the mouse Xist gene exposes trans-effects that alter the heterochromatin of the inactive X chromosome and the replication time and DNA stability of both X chromosomes.Two breakpoint clusters at fragile site FRA3B form phased nucleosomes.Intracellular signal transduction and modification of the tumor microenvironment induced by RET/PTCs in papillary thyroid carcinoma.A genome-wide analysis of common fragile sites: what features determine chromosomal instability in the human genome?The role of fragile sites in sporadic papillary thyroid carcinoma Replication timing as an epigenetic mark Common fragile sites are characterized by histone hypoacetylation.Molecular characterization of common fragile sites as a strategy to discover cancer susceptibility genes.Interplay between genetic and epigenetic factors governs common fragile site instability in cancer.Cloning and characterization of the common fragile site FRA6F harboring a replicative senescence gene and frequently deleted in human tumors.Perturbations in the Replication Program Contribute to Genomic Instability in Cancer.Enhanced flexibility and aphidicolin-induced DNA breaks near mammalian replication origins: implications for replicon mapping and chromosome fragility.Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability.Synchronization of interphase events depends neither on mitosis nor on cdk1 Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR.Sites of genetic instability in mitosis and cancer.Impaired replication dynamics at the FRA3B common fragile site.FRA3B and other common fragile sites: the weakest links.Fragile sites are preferential targets for integrations of MLV vectors in gene therapy.Interplay between ATM and ATR in the regulation of common fragile site stability.Genome instability at common fragile sites: searching for the cause of their instability

P2860

Q24622097-DF5408E2-C6F2-4C61-A434-52E6851DEC7E Q24653358-96626B46-5FEB-47E6-978B-64C88D71C0E5 Q24677893-9F435363-0A7F-4CBE-B816-FE7BBC2C29B4 Q26825040-A4953EB6-4395-4962-BF7A-D2922069917D Q33392400-067EE392-72E3-471C-A07F-FE545DA32243 Q33404454-9AF63C99-825E-46D8-BA79-9123722591B0 Q33693748-DC38A103-8482-41F6-98E5-8927199EFF96 Q33712256-8555BDA7-A2DD-47A2-8923-D3BB4CE4B272 Q33792630-24F4ACC3-781D-4596-A510-EF924AD2FF80 Q33871196-5831CA3A-C2E0-4A5B-A4B7-3EDF8E9C3FA7 Q33960440-5679D8E3-B1B3-43A6-99D5-657B3369DFC3 Q34152853-E3E889D3-C1D5-4562-90EF-A8E49F133F0F Q34212683-F316900F-5505-4EB6-BBA0-20165BBBDF00 Q34990644-0DEAF3D7-D2A2-48CE-8A57-C1480DE228AB Q35143751-1E29DA32-00A4-41F4-A8EC-140DC4EB03E1 Q35157225-BAFF98A0-68BE-4D44-A930-D5E733292FE0 Q35175983-3D564F0B-A88B-4312-97B6-2AD3D1AFF6DD Q35574244-F46A6C8F-054A-48D5-9FD0-7E5512453D2B Q35977327-7B851D55-1272-4D72-AF4E-95C841E9859D Q36021725-E7CC282E-B97C-45F5-BFEC-14ED7B6C9BB4 Q36063579-E0B69C6A-B9C6-4698-B8F7-252201D5C0B3 Q37208139-F1D130A9-9FEC-46FC-87C4-F63F7623F41D Q37411779-7D935EF3-9C52-4C2F-90AD-98ED435F4DC9 Q38250822-1819EC78-90D8-49D5-815A-957C15361FDB Q38258279-D8E38E1B-783E-45E6-93AC-C9065667673E Q38495093-7EDDB8B8-4332-4F38-9246-BC5CB55DD953 Q39354510-BD590CE0-4BDD-4D91-A151-5AA9B3F05672 Q39607399-3D651222-11D5-4A84-888C-D5E5CC6E6FD8 Q39705486-11704A65-8C8C-4AF4-B29A-1E8F529ACC63 Q39897230-7C87F3C3-3A07-493A-BE3C-E44247C8F531 Q40368333-1B4ED3F6-5DC7-4BA3-A16C-909FE5D59B81 Q42068168-5924E2BA-77DE-4042-A102-F3E59975400F Q42175506-52F8F19F-EB37-49A7-8932-CDBFEAD12C92 Q43922549-E4DAFAD8-529A-4C78-9DF4-047BE7C37727 Q44345959-212D72E9-A000-4F93-ADB1-748F042F017E Q46952776-4AD128A0-3FBC-48F4-B185-9832206F173D Q58920651-C9B508C5-5D53-40A6-B797-9C75A58F745F

P2860

Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosomal instability.

http://www.wikidata.org/entity/Q33963998

description

2000 nî lūn-bûn

@nan

2000 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2000年の論文

@ja

2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

Replication delay along FRA7H, ...... ds to chromosomal instability.

@ast

Replication delay along FRA7H, ...... ds to chromosomal instability.

@en

type

label

Replication delay along FRA7H, ...... ds to chromosomal instability.

@ast

Replication delay along FRA7H, ...... ds to chromosomal instability.

@en

prefLabel

Replication delay along FRA7H, ...... ds to chromosomal instability.

@ast

Replication delay along FRA7H, ...... ds to chromosomal instability.

@en

P1433

Q33963998-255028BE-CCC1-4AEE-98F7-5B1ACADC6095

P1476

Q33963998-BB66380B-C2CA-440A-BC2A-FB68E3AD84B4

P2093

Q33963998-19C57795-2CE0-4940-B7F9-A89EB1AAE28A

Q33963998-2E852F04-4FC3-4FBD-BED3-37FADBE15B6C

Q33963998-6CCFC3CE-48BE-42EE-9282-64B9837EDDD3

Q33963998-75F7070A-9E85-4AE9-B130-D12E49C3F652

Q33963998-8F4D1CF9-6487-4495-ACD5-CEFF53BEE496

Q33963998-9545B766-0995-476C-B0FC-209E2AC51605

P2860

Q33963998-00B710EC-A455-4D34-8DEB-E3D385A75BA5

Q33963998-017A086D-45FC-4AEB-A5F1-A265F6E98780

Q33963998-0C29162C-54AB-4026-B372-FA5DDFD38BAF

Q33963998-14387CDC-A9C2-412E-8714-43419CEBCB23

Q33963998-148B946C-F182-49D6-862E-F311CE262AC5

Q33963998-165B2C79-00A9-40A7-8BE5-E536629871CB

Q33963998-18991276-B9DE-4BA5-96BE-9FCEE44DD918

Q33963998-1E693129-163C-4CC2-B8EC-F74B2507943D

Q33963998-1F897379-E6F7-4B79-B58E-143E4EC6D9F0

Q33963998-20A5A1E9-FB43-4B69-9905-ED1A685285E7

P304

Q33963998-CF019E00-AC18-4892-9495-61F6D8CE9E8A

P31

Q33963998-6F896D92-FAFB-4C4B-ACEB-6762A5D96FDB

P356

Q33963998-1344BB68-5C4A-4859-98D7-F9CE04ED75B4

P407

Q33963998-47CFA0EB-2C0C-4C64-8635-F04C904FFB75

P433

Q33963998-044A855A-5F1C-491B-A62F-7B7DCAAFF50F

P478

Q33963998-A7355FB4-8EF1-4C2A-863D-F768F993F89E

P577

Q33963998-99B7E556-F509-4074-B2B5-126BF2618E41

P698

Q33963998-F49D75F3-CA25-44A2-88EB-F4049A11ED5F

P932

Q33963998-9A7EAA21-A847-46FC-9E9E-1E4935509EAB

P356

MCB.20.12.4420-4427.2000

P1433

Molecular and Cellular Biology

P1476

Replication delay along FRA7H, ...... ds to chromosomal instability.

@en

P2093

A Darvasi

http://www.w3.org/2001/XMLSchema#string

A Hellman

http://www.w3.org/2001/XMLSchema#string

A Rahat

http://www.w3.org/2001/XMLSchema#string

B Kerem

http://www.w3.org/2001/XMLSchema#string

L C Tsui

http://www.w3.org/2001/XMLSchema#string

S W Scherer

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of the cystic fibrosis gene: chromosome walking and jumping

High-resolution analysis of DNA replication domain organization across an R/G-band boundary

DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes

FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: direct evidence for the coincidence of viral integration sites and fragile sites

Association of a chromosome deletion syndrome with a fragile site within the proto-oncogene CBL2

Human chromosomal fragile site FRA16B is an amplified AT-rich minisatellite repeat

Chromosome bands, their chromatin flavors, and their functional features

A general protocol for evaluating the specific effects of DNA replication inhibitors.

Identification of the gene FMR2, associated with FRAXE mental retardation.

Fragile sites-cytogenetic similarity with molecular diversity.

P304

4420-4427

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/MCB.20.12.4420-4427.2000

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

20

http://www.w3.org/2001/XMLSchema#string

P577

2000-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

10825205

http://www.w3.org/2001/XMLSchema#string

P932

85809

http://www.w3.org/2001/XMLSchema#string