Cloning and characterization of the common fragile site FRA6F harboring a replicative senescence gene and frequently deleted in human tumors.
about
A BEN-domain-containing protein associates with heterochromatin and represses transcriptionGene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.Inhibition of topoisomerase I prevents chromosome breakage at common fragile sitesMolecular basis for expression of common and rare fragile sitesCommon fragile sites: genomic hotspots of DNA damage and carcinogenesisBRCA1 is required for common-fragile-site stability via its G2/M checkpoint functionGene synteny comparisons between different vertebrates provide new insights into breakage and fusion events during mammalian karyotype evolutionVariability in the incidence of miRNAs and genes in fragile sites and the role of repeats and CpG islands in the distribution of genetic material.Mechanisms of genomic instabilities underlying two common fragile-site-associated loci, PARK2 and DMD, in germ cell and cancer cell linesPremature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites.Are common fragile sites merely structural domains or highly organized "functional" units susceptible to oncogenic stress?Laser ionization mass spectrometry in oral squamous cell carcinoma.Common fragile sites are conserved features of human and mouse chromosomes and relate to large active genes.Schizophrenia, cancer and obstetric complications in an evolutionary perspective-an empirically based hypothesisA Synthetic Lethal Screen Identifies DNA Repair Pathways that Sensitize Cancer Cells to Combined ATR Inhibition and Cisplatin Treatments.Is mammalian chromosomal evolution driven by regions of genome fragility?Chromosomal instability in oral cancer cells.Replication stress induces tumor-like microdeletions in FHIT/FRA3BDNA polymerases and cancer.Critical pathways in cellular senescence and immortalization revealed by gene expression profiling.The role of DNA damage response pathways in chromosome fragility in Fragile X syndrome.Translesion DNA synthesis in the context of cancer research.Molecular characterization of common fragile sites as a strategy to discover cancer susceptibility genes.Genome position and gene amplificationOncogene-induced replication stress preferentially targets common fragile sites in preneoplastic lesions. A genome-wide study.Characterization of chromosomal translocation breakpoint sequences in solid tumours: "an in silico analysis".Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma.Significant Role of Segmental Duplications and SIDD Sites in Chromosomal Translocations of Hematological Malignancies: A Multi-parametric Bioinformatic Analysis.
P2860
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P2860
Cloning and characterization of the common fragile site FRA6F harboring a replicative senescence gene and frequently deleted in human tumors.
description
2002 nî lūn-bûn
@nan
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Cloning and characterization o ...... ently deleted in human tumors.
@en
type
label
Cloning and characterization o ...... ently deleted in human tumors.
@en
prefLabel
Cloning and characterization o ...... ently deleted in human tumors.
@en
P2093
P2860
P356
P1433
P1476
Cloning and characterization o ...... ently deleted in human tumors.
@en
P2093
Chiara Magnanini
Cristina Morelli
David I Smith
Efthimia Karayianni
Erik Thorland
Giuseppe Barbanti-Brodano
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205573
P407
P577
2002-10-01T00:00:00Z
P5875
P6179
1016592737