How cyclin A destruction escapes the spindle assembly checkpoint.
about
Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complexAPC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachmentRegulation of kinetochore-microtubule attachments through homeostatic control during mitosisQuantitative framework for ordered degradation of APC/C substrates.Hypersensitivity to DNA damage in antephase as a safeguard for genome stability.Spatiotemporal regulation of the anaphase-promoting complex in mitosisAssembly of Drosophila centromeric chromatin proteins during mitosisThe spindle assembly checkpoint works like a rheostat rather than a toggle switchMultiple mechanisms determine the order of APC/C substrate degradation in mitosis.Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.Changes in Ect2 localization couple actomyosin-dependent cell shape changes to mitotic progressionA meiosis-specific form of the APC/C promotes the oocyte-to-embryo transition by decreasing levels of the Polo kinase inhibitor matrimony.The biochemistry of mitosisA data-driven, mathematical model of mammalian cell cycle regulation.Cyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition.Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregationMitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint.State of the APC/C: organization, function, and structure.TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth.Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation.APOLLON protein promotes early mitotic CYCLIN A degradation independent of the spindle assembly checkpoint.Cks1: Structure, Emerging Roles and Implications in Multiple CancersSubstrate-specific regulation of ubiquitination by the anaphase-promoting complex.Phosphatases: providing safe passage through mitotic exit.The ubiquitin proteasome system - implications for cell cycle control and the targeted treatment of cancer.Panta rhei: the APC/C at steady state.Signalling dynamics in the spindle checkpoint response.Delayed APC/C activation extends the first mitosis of mouse embryos.Transcriptional intermediary factor 1γ binds to the anaphase-promoting complex/cyclosome and promotes mitosis.The ABBA motif binds APC/C activators and is shared by APC/C substrates and regulatorsHistone deacetylase 3 regulates cyclin A stability.How APC/C-Cdc20 changes its substrate specificity in mitosis.Co-activator independent differences in how the metaphase and anaphase APC/C recognise the same substrate.Cyclin A2 modulates kinetochore-microtubule attachment in meiosis II.Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C).Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability.The PP2AB56 phosphatase promotes the association of Cdc20 with APC/C in mitosis.How mitosis keeps itself in order.Slipping past the spindle assembly checkpoint.
P2860
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P2860
How cyclin A destruction escapes the spindle assembly checkpoint.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
How cyclin A destruction escapes the spindle assembly checkpoint.
@ast
How cyclin A destruction escapes the spindle assembly checkpoint.
@en
How cyclin A destruction escapes the spindle assembly checkpoint.
@nl
type
label
How cyclin A destruction escapes the spindle assembly checkpoint.
@ast
How cyclin A destruction escapes the spindle assembly checkpoint.
@en
How cyclin A destruction escapes the spindle assembly checkpoint.
@nl
prefLabel
How cyclin A destruction escapes the spindle assembly checkpoint.
@ast
How cyclin A destruction escapes the spindle assembly checkpoint.
@en
How cyclin A destruction escapes the spindle assembly checkpoint.
@nl
P2860
P356
P1476
How cyclin A destruction escapes the spindle assembly checkpoint.
@en
P2093
Barbara Di Fiore
P2860
P304
P356
10.1083/JCB.201001083
P407
P577
2010-08-01T00:00:00Z