Transfection of fibroblasts by cloned Abelson murine leukemia virus DNA and recovery of transmissible virus by recombination with helper virus.
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Evidence for preferential copackaging of Moloney murine leukemia virus genomic RNAs transcribed in the same chromosomal siteThe cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene productsHormone-conditional transformation by fusion proteins of c-Abl and its transforming variantsDeletion of an N-terminal regulatory domain of the c-abl tyrosine kinase activates its oncogenic potentialN-terminal mutations activate the leukemogenic potential of the myristoylated form of c-ablEvidence that retroviral transduction is mediated by DNA not by RNA.Retroviral transduction of oncogenic sequences involves viral DNA instead of RNA.Mutations in the cytoplasmic domain of EGF receptor affect EGF binding and receptor internalization.Abelson transformed fibroblasts lacking the EGF receptor are not tumourigenic in nude mice.Abelson murine leukemia virus variants with increased oncogenic potential.Oncogenic v-Abl tyrosine kinase can inhibit or stimulate growth, depending on the cell context.Transformation of mammalian fibroblasts and macrophages in vitro by a murine retrovirus encoding an avian v-myc oncogene.Isolation of temperature-sensitive Abelson virus mutants by site-directed mutagenesisIsolation of temperature-sensitive tyrosine kinase mutants of v-abl oncogene by screening with antibodies for phosphotyrosine.Insertional mutagenesis of the Abelson murine leukemia virus genome: identification of mutants with altered kinase activity and defective transformation ability.Biologic and molecular characterization of two newly isolated ras-containing murine leukemia viruses.Nuclear localization of v-Abl leads to complex formation with cyclic AMP response element (CRE)-binding protein and transactivation through CRE motifs.Dominant transformation by mutated human ras genes in vitro requires more than 100 times higher expression than is observed in cancersBCR-ABL and v-abl oncogenes induce distinct patterns of thymic lymphoma involving different lymphocyte subsets.Mutated alpha subunit of the Gq protein induces malignant transformation in NIH 3T3 cellsHigh incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene.Carboxyl-terminal determinants of Abelson protein important for lymphoma induction.The transforming domain alone of the latent membrane protein of Epstein-Barr virus is toxic to cells when expressed at high levelsOnly site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity.The minimum transforming region of v-abl is the segment encoding protein-tyrosine kinase.Protein stabilization explains the gag requirement for transformation of lymphoid cells by Abelson murine leukemia virusSite-directed deletions of Abelson murine leukemia virus define 3' sequences essential for transformation and lethality.Cloning and analysis of reverse transcript P160 genomes of Abelson murine leukemia virusAdaptation of a retrovirus as a eucaryotic vector transmitting the herpes simplex virus thymidine kinase gene.Retrovirus transduction: generation of infectious retroviruses expressing dominant and selectable genes is associated with in vivo recombination and deletion events.Retroviral recombination during reverse transcription.Murine leukemia virus RNA dimerization is coupled to transcription and splicing processes.The human leukemia oncogene bcr-abl abrogates the anchorage requirement but not the growth factor requirement for proliferationCharacterization of unintegrated retroviral DNA with long terminal repeat-associated cell-derived inserts.Abelson murine leukemia virus induces platelet-derived growth factor-independent fibroblast growth: correlation with kinase activity and dissociation from full morphologic transformationTransfer of genes into embryonal carcinoma cells by retrovirus infection: efficient expression from an internal promoter.
P2860
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P2860
Transfection of fibroblasts by cloned Abelson murine leukemia virus DNA and recovery of transmissible virus by recombination with helper virus.
description
1982 nî lūn-bûn
@nan
1982 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1982 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1982年の論文
@ja
1982年論文
@yue
1982年論文
@zh-hant
1982年論文
@zh-hk
1982年論文
@zh-mo
1982年論文
@zh-tw
1982年论文
@wuu
name
Transfection of fibroblasts by ...... combination with helper virus.
@ast
Transfection of fibroblasts by ...... combination with helper virus.
@en
Transfection of fibroblasts by ...... combination with helper virus.
@nl
type
label
Transfection of fibroblasts by ...... combination with helper virus.
@ast
Transfection of fibroblasts by ...... combination with helper virus.
@en
Transfection of fibroblasts by ...... combination with helper virus.
@nl
prefLabel
Transfection of fibroblasts by ...... combination with helper virus.
@ast
Transfection of fibroblasts by ...... combination with helper virus.
@en
Transfection of fibroblasts by ...... combination with helper virus.
@nl
P2093
P2860
P1433
P1476
Transfection of fibroblasts by ...... ecombination with helper virus
@en
P2093
P2860
P304
P407
P577
1982-01-01T00:00:00Z