Processing of topoisomerase I cleavable complexes into DNA damage by transcription.
about
Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PKRole for nucleolin/Nsr1 in the cellular localization of topoisomerase I.TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivoGenome-wide transcriptional effects of the anti-cancer agent camptothecinPhosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal deathThe SUMO pathway is required for selective degradation of DNA topoisomerase IIbeta induced by a catalytic inhibitor ICRF-193(1)DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial InhibitionDNA topoisomerase I inhibition by camptothecin induces escape of RNA polymerase II from promoter-proximal pause site, antisense transcription and histone acetylation at the human HIF-1alpha gene locus.Cellular processing determinants for the activation of damage signals in response to topoisomerase I-linked DNA breakage.Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex.Transcription-dependent activation of ataxia telangiectasia mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase I poisonTyrosyl-DNA-phosphodiesterases (TDP1 and TDP2).A human topoisomerase I cleavage complex is recognized by an additional human topisomerase I molecule in vitro.Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff.Relationship of DNA damage signaling to DNA replication following treatment with DNA topoisomerase inhibitors camptothecin/topotecan, mitoxantrone, or etoposideTranscription blockage by bulky end termini at single-strand breaks in the DNA template: differential effects of 5' and 3' adducts.Cytometric assessment of DNA damage in relation to cell cycle phase and apoptosis.Topoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae.Role for topoisomerase 1 in transcription-associated mutagenesis in yeastDNA topoisomerase II as a target for cancer chemotherapy.Transcription-dependent degradation of topoisomerase I-DNA covalent complexesPoly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells.Different mating-type-regulated genes affect the DNA repair defects of Saccharomyces RAD51, RAD52 and RAD55 mutants.Repair synthesis step involving ERCC1-XPF participates in DNA repair of the Top1-DNA damage complex.Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation.Repair of topoisomerase I-mediated DNA damage.Topoisomerase IIβ deficiency enhances camptothecin-induced apoptosis.The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cellsISG15 as a novel tumor biomarker for drug sensitivity.SUMO modification of DNA topoisomerase II: trying to get a CENse of it allSuppression of lupus nephritis and skin lesions in MRL/lpr mice by administration of the topoisomerase I inhibitor irinotecan.Hyperphosphorylation of RNA polymerase II in response to topoisomerase I cleavage complexes and its association with transcription- and BRCA1-dependent degradation of topoisomerase I.Role of oxygen radicals generated by NADPH oxidase in apoptosis induced in human leukemia cells.Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development.Transcription poisoning by Topoisomerase I is controlled by gene length, splice sites, and miR-142-3pAnti-Proliferative and Apoptosis-Inducing Effect of Theabrownin against Non-small Cell Lung Adenocarcinoma A549 Cells.Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks.Ribonucleotides and Transcription-Associated Mutagenesis in Yeast.Coordination of DNA single strand break repair.
P2860
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P2860
Processing of topoisomerase I cleavable complexes into DNA damage by transcription.
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Processing of topoisomerase I cleavable complexes into DNA damage by transcription.
@ast
Processing of topoisomerase I cleavable complexes into DNA damage by transcription.
@en
Processing of topoisomerase I cleavable complexes into DNA damage by transcription.
@nl
type
label
Processing of topoisomerase I cleavable complexes into DNA damage by transcription.
@ast
Processing of topoisomerase I cleavable complexes into DNA damage by transcription.
@en
Processing of topoisomerase I cleavable complexes into DNA damage by transcription.
@nl
prefLabel
Processing of topoisomerase I cleavable complexes into DNA damage by transcription.
@ast
Processing of topoisomerase I cleavable complexes into DNA damage by transcription.
@en
Processing of topoisomerase I cleavable complexes into DNA damage by transcription.
@nl
P2860
P356
P1476
Processing of topoisomerase I cleavable complexes into DNA damage by transcription
@en
P2860
P304
P356
10.1093/NAR/25.21.4181
P407
P50
P577
1997-11-01T00:00:00Z