The murine N-ras gene is not essential for growth and development.
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K-Ras4B phosphorylation at Ser181 is inhibited by calmodulin and modulates K-Ras activity and functionR-Ras3/M-Ras induces neuronal differentiation of PC12 cells through cell-type-specific activation of the mitogen-activated protein kinase cascade.A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol estersK-ras/PI3K-Akt signaling is essential for zebrafish hematopoiesis and angiogenesisCalmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signalingH-Ras and phosphoinositide 3-kinase cooperate to induce alpha(1,3)-fucosyltransferase VII expression in Jurkat T cellsH-Ras signaling and K-Ras signaling are differentially dependent on endocytosis.Suprachiasmatic nucleus circadian oscillatory protein, a novel binding partner of K-Ras in the membrane rafts, negatively regulates MAPK pathwayInvolvement of a small GTP-binding protein (G protein) regulator, small G protein GDP dissociation stimulator, in antiapoptotic cell survival signalingRas oncogenes: split personalitiesMASL1 induces erythroid differentiation in human erythropoietin-dependent CD34+ cells through the Raf/MEK/ERK pathwayRas history: The saga continues.A comprehensive survey of Ras mutations in cancer.Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells.Analysis of k-ras nuclear expression in fibroblasts and mesangial cellsActivated Ras alters lens and corneal development through induction of distinct downstream targets.Minireview: physiological and pathological actions of RAS in the ovary.Ras membrane orientation and nanodomain localization generate isoform diversityElevated phosphate activates N-ras and promotes cell transformation and skin tumorigenesis.Krüppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations.Control of B cell development by Ras-mediated activation of Raf.R-Ras3, a brain-specific Ras-related protein, activates Akt and promotes cell survival in PC12 cells.Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and developmentIdentification of K-ras as the major regulator for cytokine-dependent Akt activation in erythroid progenitors in vivo.Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice.A Ras by any other name.BCR-ABL but not JAK2 V617F inhibits erythropoiesis through the Ras signal by inducing p21CIP1/WAF1.The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras.A plausible function of the prion protein: conjectures and a hypothesis.Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutationsCellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38Nras overexpression results in granulocytosis, T-cell expansion and early lethality in mice.Ras isoform-specific signaling: location, location, location.Preclinical efficacy of MEK inhibition in Nras-mutant AML.In TCR-stimulated T-cells, N-ras regulates specific genes and signal transduction pathwaysSerum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycleWhile K-ras is essential for mouse development, expression of the K-ras 4A splice variant is dispensable.Reversible, interrelated mRNA and miRNA expression patterns in the transcriptome of Rasless fibroblasts: functional and mechanistic implicationsRb and N-ras function together to control differentiation in the mouse.K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
P2860
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P2860
The murine N-ras gene is not essential for growth and development.
description
1995 nî lūn-bûn
@nan
1995 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The murine N-ras gene is not essential for growth and development.
@ast
The murine N-ras gene is not essential for growth and development.
@en
The murine N-ras gene is not essential for growth and development.
@nl
type
label
The murine N-ras gene is not essential for growth and development.
@ast
The murine N-ras gene is not essential for growth and development.
@en
The murine N-ras gene is not essential for growth and development.
@nl
prefLabel
The murine N-ras gene is not essential for growth and development.
@ast
The murine N-ras gene is not essential for growth and development.
@en
The murine N-ras gene is not essential for growth and development.
@nl
P2093
P2860
P356
P1476
The murine N-ras gene is not essential for growth and development.
@en
P2093
A Pellicer
R Kucherlapati
W Edelmann
P2860
P304
P356
10.1073/PNAS.92.5.1709
P407
P577
1995-02-01T00:00:00Z