Cytokine production and inflammation drive autophagy in the tumor microenvironment: role of stromal caveolin-1 as a key regulator.
about
Interactions between Autophagy and Inhibitory CytokinesCancer stem cell metabolismCilia in autophagy and cancerCaveolin-1, a stress-related oncotarget, in drug resistanceOncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discoveryUnderstanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironmentInterplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapyCancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumorsCrosstalk between apoptosis and autophagy: molecular mechanisms and therapeutic strategies in cancer.Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer".Understanding the metabolic basis of drug resistance: therapeutic induction of the Warburg effect kills cancer cells.The role of autophagy induced by tumor microenvironment in different cells and stages of cancerCaveolin-1, cellular senescence and age-related diseases.Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cellsIs cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolismCritical role of CAV1/caveolin-1 in cell stress responses in human breast cancer cells via modulation of lysosomal function and autophagy.Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth.Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drugAutophagy in pancreatic cancer pathogenesis and treatmentTumor suppression by p53 without apoptosis and senescence: conundrum or rapalog-like gerosuppression?Proteomic identification of prognostic tumour biomarkers, using chemotherapy-induced cancer-associated fibroblastsCDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis.Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth.Altered APP processing in insulin-resistant conditions is mediated by autophagosome accumulation via the inhibition of mammalian target of rapamycin pathway.Interaction of caveolin-1 with ATG12-ATG5 system suppresses autophagy in lung epithelial cells.GEN-27, a Newly Synthetic Isoflavonoid, Inhibits the Proliferation of Colon Cancer Cells in Inflammation Microenvironment by Suppressing NF-κB Pathway.Autophagy is involved in TGF-β1-induced protective mechanisms and formation of cancer-associated fibroblasts phenotype in tumor microenvironmentCompartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis.Chloroquine inhibits HMGB1 inflammatory signaling and protects mice from lethal sepsis.PTRF/Cavin-1 decreases prostate cancer angiogenesis and lymphangiogenesis.Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4.Genetic alterations and epigenetic alterations of cancer-associated fibroblasts.Autophagy and cancer.Autophagic tumor stroma: mechanisms and roles in tumor growth and progression.Self-eating and self-defense: autophagy controls innate immunity and adaptive immunity.Autophagy-mediated regulation of macrophages and its applications for cancer.Inflammatory Signaling Cascades and Autophagy in Cancer.
P2860
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P2860
Cytokine production and inflammation drive autophagy in the tumor microenvironment: role of stromal caveolin-1 as a key regulator.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Cytokine production and inflam ...... caveolin-1 as a key regulator.
@ast
Cytokine production and inflam ...... caveolin-1 as a key regulator.
@en
type
label
Cytokine production and inflam ...... caveolin-1 as a key regulator.
@ast
Cytokine production and inflam ...... caveolin-1 as a key regulator.
@en
prefLabel
Cytokine production and inflam ...... caveolin-1 as a key regulator.
@ast
Cytokine production and inflam ...... caveolin-1 as a key regulator.
@en
P2093
P2860
P50
P356
P1433
P1476
Cytokine production and inflam ...... caveolin-1 as a key regulator.
@en
P2093
Neal Flomenberg
Richard G Pestell
P2860
P304
P356
10.4161/CC.10.11.15674
P50
P577
2011-06-01T00:00:00Z