Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors.
about
The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substratesIn vitro and in vivo activities of 1-hydroxy-2-alkyl-4(1H)quinolone derivatives against Toxoplasma gondii.Variation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain functionArrested oocyst maturation in Plasmodium parasites lacking type II NADH:ubiquinone dehydrogenase.Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex.Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors.How mitochondrial dysfunction affects zebrafish development and cardiovascular function: an in vivo model for testing mitochondria-targeted drugs.A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activityTarget identification and validation of novel antimalarials.Mitochondrial type II NAD(P)H dehydrogenases in fungal cell deathExpression, purification, crystallization and preliminary X-ray diffraction analysis of a type II NADH:quinone oxidoreductase from the human pathogen Staphylococcus aureus.Two internal type II NADH dehydrogenases of Toxoplasma gondii are both required for optimal tachyzoite growth.Screening of potential targets in Plasmodium falciparum using stage-specific metabolic network analysis.A Dedicated Type II NADPH Dehydrogenase Performs the Penultimate Step in the Biosynthesis of Vitamin K1 in Synechocystis and Arabidopsis.Type II NADH dehydrogenase inhibitor 1-hydroxy-2-dodecyl-4(1H)quinolone leads to collapse of mitochondrial inner-membrane potential and ATP depletion in Toxoplasma gondii.
P2860
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P2860
Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Type II NADH dehydrogenase of ...... falciparum and its inhibitors.
@ast
Type II NADH dehydrogenase of ...... falciparum and its inhibitors.
@en
type
label
Type II NADH dehydrogenase of ...... falciparum and its inhibitors.
@ast
Type II NADH dehydrogenase of ...... falciparum and its inhibitors.
@en
prefLabel
Type II NADH dehydrogenase of ...... falciparum and its inhibitors.
@ast
Type II NADH dehydrogenase of ...... falciparum and its inhibitors.
@en
P2093
P2860
P1476
Type II NADH dehydrogenase of ...... falciparum and its inhibitors.
@en
P2093
Carolyn K Dong
Jeffrey D Dvorin
Jimmy C Yang
Jon Clardy
Vishal Patel
P2860
P304
P356
10.1016/J.BMCL.2008.11.071
P407
P577
2008-11-24T00:00:00Z