Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease.
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Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor proteinLysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin SInsulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivoOn cognitive ecology and the environmental factors that promote Alzheimer disease: lessons from Octodon degus (Rodentia: Octodontidae)Diabetes mellitus accelerates Aβ pathology in brain accompanied by enhanced GAβ generation in nonhuman primatesNonhuman primate models of Alzheimer-like cerebral proteopathyNeuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer diseaseNeuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease.How ionic strength affects the conformational behavior of human and rat beta amyloids--a computational studyAlzheimer's disease abeta vaccine reduces central nervous system abeta levels in a non-human primate, the Caribbean vervet.Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation.Increased amyloidogenic secretion in cerebellar granule cells undergoing apoptosisMicroinjection of synthetic amyloid beta-protein in monkey cerebral cortex fails to produce acute neurotoxicitySynaptic pathology and glial responses to neuronal injury precede the formation of senile plaques and amyloid deposits in the aging cerebral cortex.Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation.Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer's disease.Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals.Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis.The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum.Hyperpolarization-activated cyclic nucleotide gated channels: a potential molecular link between epileptic seizures and Aβ generation in Alzheimer's diseaseLifespan profiles of Alzheimer's disease-associated genes and products in monkeys and miceEvidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities.Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD.Identification of a stable fragment of the Alzheimer amyloid precursor containing the beta-protein in brain microvessels.Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavageSelective ectodomain phosphorylation and regulated cleavage of beta-amyloid precursor proteinNovel N-terminal cleavage of APP precludes Abeta generation in ACAT-defective AC29 cells.Beta/A4 proteinlike immunoreactive granular structures in the brain of senescence-accelerated mouseCortical neurons transgenic for human Abeta40 or Abeta42 have similar vulnerability to apoptosis despite their different amyloidogenic properties.Co-localization and distribution of cerebral APP and SP1 and its relationship to amyloidogenesis.Neurodegenerative disease biomarkers Aβ1-40, Aβ1-42, tau, and p-tau181 in the vervet monkey cerebrospinal fluid: Relation to normal aging, genetic influences, and cerebral amyloid angiopathy.Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer's disease model mice and macaques.The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade.New nucleotide sequence data on the EMBL File Server
P2860
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P2860
Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Homology of the amyloid beta p ...... idosis in Alzheimer's disease.
@ast
Homology of the amyloid beta p ...... idosis in Alzheimer's disease.
@en
type
label
Homology of the amyloid beta p ...... idosis in Alzheimer's disease.
@ast
Homology of the amyloid beta p ...... idosis in Alzheimer's disease.
@en
prefLabel
Homology of the amyloid beta p ...... idosis in Alzheimer's disease.
@ast
Homology of the amyloid beta p ...... idosis in Alzheimer's disease.
@en
P2860
P1476
Homology of the amyloid beta p ...... oidosis in Alzheimer's disease
@en
P2093
D J Selkoe
M B Podlisny
P2860
P304
P407
P577
1991-06-01T00:00:00Z