about
Understanding mammalian genetic systems: the challenge of phenotyping in the mouseA conditional knockout resource for the genome-wide study of mouse gene functionGene targeting in the rat: advances and opportunitiesVirtues and limitations of the preimplantation mouse embryo as a model systemGeneration of a Tph2 Conditional Knockout Mouse Line for Time- and Tissue-Specific Depletion of Brain SerotoninHIV-1 proviral DNA excision using an evolved recombinaseSynthetic microRNA-mediated downregulation of Nogo-A in transgenic rats reveals its role as regulator of synaptic plasticity and cognitive functionLAHEDES: the LAGLIDADG homing endonuclease database and engineering serverModeling chromosomes in mouse to explore the function of genes, genomic disorders, and chromosomal organizationLarge-scale, saturating insertional mutagenesis of the mouse genomeCharacterization of parameters required for effective use of tamoxifen-regulated recombination.The expanding role of mouse genetics for understanding human biology and diseaseA high-speed congenic strategy using first-wave male germ cellsThe effect on intracytoplasmic sperm injection outcome of genotype, male germ cell stage and freeze-thawing in miceSingle-stranded heteroduplex intermediates in lambda Red homologous recombination.Dual RMCE for efficient re-engineering of mouse mutant alleles.A pink mouse reports the switch from red to green fluorescence upon Cre-mediated recombinationVariability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice.Conditional transgenic mouse models: from the basics to genome-wide sets of knockouts and current studies of tissue regeneration.The molecular and cellular biology of enhanced cognition.Technical approaches for mouse models of human diseaseValidation of simple sequence length polymorphism regions of commonly used mouse strains for marker assisted speed congenics screening.Isolation of Novel CreERT2-Driver Lines in Zebrafish Using an Unbiased Gene Trap ApproachReversible gene knockdown in mice using a tight, inducible shRNA expression system.A recombineering based approach for high-throughput conditional knockout targeting vector construction.Flp and Cre expressed from Flp-2A-Cre and Flp-IRES-Cre transcription units mediate the highest level of dual recombinase-mediated cassette exchangeTissue-specific and reversible RNA interference in transgenic mice.Comparison of male chimeric mice generated from microinjection of JM8.N4 embryonic stem cells into C57BL/6J and C57BL/6NTac blastocysts.Approaches to lipid metabolism gene identification and characterization in the postgenomic era.Vika/vox, a novel efficient and specific Cre/loxP-like site-specific recombination system.Building blood vessels--stem cell models in vascular biology.Cancer-specific binary expression system activated in mice by bacteriophage HK022 Integrase.Possible pitfalls investigating cell death responses in genetically engineered mouse models and derived cell lines.Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats.Protein tyrosine phosphatases: functional inferences from mouse models and human diseases.Discovery of Nigri/nox and Panto/pox site-specific recombinase systems facilitates advanced genome engineeringHuman embryonic stem cells: lessons from stem cell niches in vivo.Stress and stem cells.In ovo RNAi opens new possibilities for temporal and spatial control of gene silencing during development of the vertebrate nervous system.Interpreting neonatal lethal phenotypes in mouse mutants: insights into gene function and human diseases.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Current issues in mouse genome engineering.
@ast
Current issues in mouse genome engineering.
@en
type
label
Current issues in mouse genome engineering.
@ast
Current issues in mouse genome engineering.
@en
prefLabel
Current issues in mouse genome engineering.
@ast
Current issues in mouse genome engineering.
@en
P2860
P356
P1433
P1476
Current issues in mouse genome engineering.
@en
P2093
A Francis Stewart
Stefan Glaser
P2860
P2888
P304
P356
10.1038/NG1668
P407
P577
2005-11-01T00:00:00Z