Transgenic rearranged T cell receptor gene inhibits lymphadenopathy and accumulation of CD4-CD8-B220+ T cells in lpr/lpr mice
about
Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contactsCorrection of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice.A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease.B-cell tolerance defects in the B6.Aec1/2 mouse model of Sjögren's syndrome.Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr miceAutoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene.Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice.T cells with gamma/delta T cell receptors (TCR) of intestinal type are preferentially expanded in TCR-alpha-deficient lpr mice.Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cellsNormal thymocyte negative selection in TRAIL-deficient mice.Autoimmunity: twenty years in the Fas laneGld and lpr mice: single gene mutant models for failed self tolerance.Cellular interactions in the lpr and gld models of systemic autoimmunity.Abnormal thymic maturation and lymphoproliferation in MRL-Fas lpr/lpr mice can be partially reversed by synthetic oligonucleotides: implications for systemic lupus erythematosus and autoimmune lymphoproliferative syndrome.
P2860
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P2860
Transgenic rearranged T cell receptor gene inhibits lymphadenopathy and accumulation of CD4-CD8-B220+ T cells in lpr/lpr mice
description
1990 nî lūn-bûn
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1990年の論文
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1990年学术文章
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name
Transgenic rearranged T cell r ...... -B220+ T cells in lpr/lpr mice
@ast
Transgenic rearranged T cell r ...... -B220+ T cells in lpr/lpr mice
@en
type
label
Transgenic rearranged T cell r ...... -B220+ T cells in lpr/lpr mice
@ast
Transgenic rearranged T cell r ...... -B220+ T cells in lpr/lpr mice
@en
prefLabel
Transgenic rearranged T cell r ...... -B220+ T cells in lpr/lpr mice
@ast
Transgenic rearranged T cell r ...... -B220+ T cells in lpr/lpr mice
@en
P2093
P2860
P356
P1476
Transgenic rearranged T cell r ...... -B220+ T cells in lpr/lpr mice
@en
P2093
P2860
P304
P356
10.1084/JEM.172.6.1805
P407
P577
1990-12-01T00:00:00Z