Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain.
about
Association of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transductionTranscriptional control of CD4 and CD8 coreceptor expression during T cell developmentStructural Basis of the CD8 /MHC Class I Interaction: Focused Recognition Orients CD8 to a T Cell Proximal PositionCD3 delta establishes a functional link between the T cell receptor and CD8CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers.Lineage diversion of T cell receptor transgenic thymocytes revealed by lineage fate mapping.Role of CD8+ T cells and lymphoid dendritic cells in protection from ocular herpes simplex virus 1 challenge in immunized mice.Antigen-specific clonal expansion and cytolytic effector function of CD8+ T lymphocytes depend on the transcription factor Bcl11b.Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor.Sialic acid capping of CD8beta core 1-O-glycans controls thymocyte-major histocompatibility complex class I interaction.Facilitation of beta selection and modification of positive selection in the thymus of PD-1-deficient miceThe light and dark sides of intestinal intraepithelial lymphocytesCD8α dendritic cells drive establishment of HSV-1 latencyHD mice: a novel mouse mutant with a specific defect in the generation of CD4(+) T cells.High- and low-affinity single-peptide/MHC ligands have distinct effects on the development of mucosal CD8alphaalpha and CD8alphabeta T lymphocytesCD8 beta chain influences CD8 alpha chain-associated Lck kinase activity.Human CD8 transgene regulation of HLA recognition by murine T cells.The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells.Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cellsCritical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimersCD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding.CD3 ligation on immature thymocytes generates antagonist-like signals appropriate for CD8 lineage commitment, independently of T cell receptor specificity.An opposite pattern of selection of a single T cell antigen receptor in the thymus and among intraepithelial lymphocytes.Structural and biophysical insights into the role of CD4 and CD8 in T cell activation.CD8 lineage commitment in the absence of CD8.Role of coreceptors in positive selection and lineage commitment.Duality of the murine CD8 compartment.Biosynthesis of major histocompatibility complex molecules and generation of T cells in Ii TAP1 double-mutant mice.TL and CD8αα: Enigmatic partners in mucosal immunity.Coreceptors and adapter proteins in T-cell signaling.IL-21 can supplement suboptimal Lck-independent MAPK activation in a STAT-3-dependent manner in human CD8(+) T cellsGlu227-->Lys substitution in the acidic loop of major histocompatibility complex class I alpha 3 domain distinguishes low avidity CD8 coreceptor and avidity-enhanced CD8 accessory functions.Stochastic coreceptor shut-off is restricted to the CD4 lineage maturation pathway.Glycosylation and the function of the T cell co-receptor CD8.Negative selection of the T-cell repertoire: where and when does it occur?
P2860
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P2860
Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Disruption of T lymphocyte pos ...... ce lacking the CD8 beta chain.
@en
type
label
Disruption of T lymphocyte pos ...... ce lacking the CD8 beta chain.
@en
prefLabel
Disruption of T lymphocyte pos ...... ce lacking the CD8 beta chain.
@en
P1433
P1476
Disruption of T lymphocyte pos ...... ce lacking the CD8 beta chain.
@en
P2093
P304
P356
10.1016/1074-7613(94)90079-5
P407
P577
1994-07-01T00:00:00Z