about
A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1) in mouse liverDisruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell deathIFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagyLocalisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cellsCoordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuolePhosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulenceThe activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondiiInterferon-gamma is a critical modulator of CB(2) cannabinoid receptor signaling during neuropathic painAutophagy and pattern recognition receptors in innate immunityAutophagy in immunity against mycobacterium tuberculosis: a model system to dissect immunological roles of autophagyInflammatory stimuli reprogram macrophage phagocytosis to macropinocytosis for the rapid elimination of pathogensThe Evolutionarily Dynamic IFN-Inducible GTPase Proteins Play Conserved Immune Functions in Vertebrates and CephalochordatesStructure of the Roc–COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinaseRegulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondiiRegulation of macrophage motility by Irgm1Repeated BCG treatment of mouse bladder selectively stimulates small GTPases and HLA antigens and inhibits single-spanning uroplakins.Modeling infectious disease in mice: co-adaptation and the role of host-specific IFNgamma responses.Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.Interferon-induced genes of the expanded IFIT family show conserved antiviral activities in non-mammalian speciesInterferon-γ-dependent control of Anaplasma phagocytophilum by murine neutrophil granulocytes.The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens.Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infectionsTranscriptome profiling of immune responses to cardiomyopathy syndrome (CMS) in Atlantic salmon.Critical coordination of innate immune defense against Toxoplasma gondii by dendritic cells responding via their Toll-like receptorsInterferon γ-induced GTPase promotes invasion of Listeria monocytogenes into trophoblast giant cells.Secretion of Antonospora (Paranosema) locustae proteins into infected cells suggests an active role of microsporidia in the control of host programs and metabolic processes.The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashionTranscriptional Profiling of Foam Cells Reveals Induction of Guanylate-Binding Proteins Following Western Diet Acceleration of Atherosclerosis in the Absence of Global Changes in Inflammation.Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection.The secreted kinase ROP18 defends Toxoplasma's border.IFN-inducible GTPases in host cell defenseCARD6 is interferon inducible but not involved in nucleotide-binding oligomerization domain protein signaling leading to NF-kappaB activation.Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replicationIRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens.The arginine-rich N-terminal domain of ROP18 is necessary for vacuole targeting and virulence of Toxoplasma gondii.Invasion and intracellular survival by protozoan parasites.Emerging themes in IFN-gamma-induced macrophage immunity by the p47 and p65 GTPase families.Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis.Mechanisms and consequences of persistence of intracellular pathogens: leishmaniasis as an example.Balance of Irgm protein activities determines IFN-gamma-induced host defense
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The interferon-inducible GTPases.
@ast
The interferon-inducible GTPases.
@en
type
label
The interferon-inducible GTPases.
@ast
The interferon-inducible GTPases.
@en
prefLabel
The interferon-inducible GTPases.
@ast
The interferon-inducible GTPases.
@en
P1476
The interferon-inducible GTPases
@en
P2093
Jonathan Howard
Sascha Martens
P304
P356
10.1146/ANNUREV.CELLBIO.22.010305.104619
P577
2006-01-01T00:00:00Z