Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor
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Modulatory roles for integrin activation and the synergy site of fibronectin during matrix assemblyPlatelet signal transduction defect with Galpha subunit dysfunction and diminished Galphaq in a patient with abnormal platelet responsesCollagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrinsAffinity modulation of platelet integrin alphaIIbbeta3 by beta3-endonexin, a selective binding partner of the beta3 integrin cytoplasmic tailA single immunoglobulin-like domain of the human neural cell adhesion molecule L1 supports adhesion by multiple vascular and platelet integrinsSer-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombastheniaMolecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognitionThe integrin VLA-2 binds echovirus 1 and extracellular matrix ligands by different mechanisms.Ligand bridging mediates integrin alpha IIb beta 3 (platelet GPIIB-IIIA) dependent homotypic and heterotypic cell-cell interactions.Ligand-dependent and -independent integrin focal contact localization: the role of the alpha chain cytoplasmic domain.Endothelial cell spreading on fibrin requires fibrinopeptide B cleavage and amino acid residues 15-42 of the beta chain.Reconstruction of integrin activation.Impaired platelet aggregation and sustained bleeding in mice lacking the fibrinogen motif bound by integrin alpha IIb beta 3.CIB1 is an endogenous inhibitor of agonist-induced integrin alphaIIbbeta3 activation.A molecular switch that controls cell spreading and retraction.Requirements for hyaluronic acid binding by CD44: a role for the cytoplasmic domain and activation by antibody.A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogenMultiple functional forms of the integrin VLA-2 can be derived from a single alpha 2 cDNA clone: interconversion of forms induced by an anti-beta 1 antibody.Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions.Evidence for the selective association of a subpopulation of GPIIb-IIIa with the actin cytoskeletons of thrombin-activated platelets.Affinity modulation of integrin alpha 5 beta 1: regulation of the functional response by soluble fibronectin.Structure/function analysis of the integrin beta 1 subunit by epitope mapping.Integrin cytoplasmic domains mediate inside-out signal transduction.Integrin beta 3 cytoplasmic tail is necessary and sufficient for regulation of alpha 5 beta 1 phagocytosis by alpha v beta 3 and integrin-associated protein.Modulation of cell migration by integrin-mediated cytoskeletal linkages and ligand-binding affinity.Muscle beta1D integrin reinforces the cytoskeleton-matrix link: modulation of integrin adhesive function by alternative splicing.Analysis of C-cadherin regulation during tissue morphogenesis with an activating antibody.Analysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3) using a reconstituted mammalian cell expression modelCritical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signalingInterchangeable alpha chain cytoplasmic domains play a positive role in control of cell adhesion mediated by VLA-4, a beta 1 integrin.Stimulation of integrin-mediated adhesion of T lymphocytes and monocytes: two mechanisms with divergent biological consequences.Glycosylation of CD44 negatively regulates its recognition of hyaluronan.Monoclonal antibodies to CD44 and their influence on hyaluronan recognition.Regulation of alpha 6 beta 1 integrin laminin receptor function by the cytoplasmic domain of the alpha 6 subunit.A VCAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture.Arg-Gly-Asp-containing peptides expose novel collagen receptors on fibroblasts: implications for wound healingThe small GTP-binding protein R-Ras can influence integrin activation by antagonizing a Ras/Raf-initiated integrin suppression pathwaySerine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin.The Pl(A2) polymorphism of integrin beta(3) enhances outside-in signaling and adhesive functions.Truncation of the cytoplasmic domain of beta3 in a variant form of Glanzmann thrombasthenia abrogates signaling through the integrin alpha(IIb)beta3 complex.
P2860
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P2860
Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Affinity modulation of the alp ...... insic property of the receptor
@ast
Affinity modulation of the alp ...... insic property of the receptor
@en
type
label
Affinity modulation of the alp ...... insic property of the receptor
@ast
Affinity modulation of the alp ...... insic property of the receptor
@en
prefLabel
Affinity modulation of the alp ...... insic property of the receptor
@ast
Affinity modulation of the alp ...... insic property of the receptor
@en
P2093
P2860
P1476
Affinity modulation of the alp ...... insic property of the receptor
@en
P2093
J C Loftus
M H Ginsberg
S J Shattil
T E O'Toole
Z M Ruggeri
P2860
P304
P577
1990-11-01T00:00:00Z