Phenotypic change from transformed to normal induced by benzoquinonoid ansamycins accompanies inactivation of p60src in rat kidney cells infected with Rous sarcoma virus.
about
Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrinsNAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinonesLigand binding to macrophage scavenger receptor-A induces urokinase-type plasminogen activator expression by a protein kinase-dependent signaling pathwayGeldanamycin: the prototype of a class of antitumor drugs targeting the heat shock protein 90 family of molecular chaperonesIntegrin function: molecular hierarchies of cytoskeletal and signaling moleculesc-Src is required for complex formation between the hepatitis C virus-encoded proteins NS5A and NS5B: a prerequisite for replication.Geldanamycin disrupts platelet-membrane structure, leading to membrane permeabilization and inhibition of platelet aggregation.Tyrosine kinase activity, cytoskeletal organization, and motility in human vascular endothelial cells.Development and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer cells.Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone.Hsp90 binds and regulates Gcn2, the ligand-inducible kinase of the alpha subunit of eukaryotic translation initiation factor 2 [corrected]Chaperones in cell cycle regulation and mitogenic signal transduction: a review.Acid activation of immediate early genes in renal epithelial cellsSensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast.Comparative Study of 17-AAG and NVP-AUY922 in Pancreatic and Colorectal Cancer Cells: Are There Common Determinants of Sensitivity?HSP90 as a new therapeutic target for cancer therapy: the story unfolds.Proposal for a role of the Hsp90/Hsp70-based chaperone machinery in making triage decisions when proteins undergo oxidative and toxic damage.Phase I trial of 17-allylamino-17-demethoxygeldanamycin in patients with advanced cancerUnder cover: causes, effects and implications of Hsp90-mediated genetic capacitance.Advances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment.Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase.Pharmacology of second messengers: a critical appraisal.Induction of in vitro differentiation of mouse embryonal carcinoma (F9) and erythroleukemia (MEL) cells by herbimycin A, an inhibitor of protein phosphorylation.Staurosporine inhibits agrin-induced acetylcholine receptor phosphorylation and aggregationBeta-actin mRNA localization is regulated by signal transduction mechanisms.Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor moleculesA balance between positive and negative signals in cytotoxic lymphocytes regulates the polarization of lipid rafts during the development of cell-mediated killingTyrosine phosphorylation is an early and specific event involved in primary keratinocyte differentiationDifferentiation of erythroid progenitor (CFU-E) cells from mouse fetal liver cells and murine erythroleukemia (TSA8) cells without proliferation.Treatment for chronic myelogenous leukemia: the long road to imatinibCisplatin abrogates the geldanamycin-induced heat shock responseNatural product inhibitors of Hsp90: potential leads for drug discoveryHSP90 inhibitor, DMAG, synergizes with radiation of lung cancer cells by interfering with base excision and ATM-mediated DNA repairHeat Shock Protein (HSP) Drug Discovery and Development: Targeting Heat Shock Proteins in Disease.P-Glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response.Changes in HER2 expression in breast cancer xenografts after therapy can be quantified using PET and (18)F-labeled affibody molecules.Effect of geldanamycin on androgen receptor function and stability.Bacterial lipopolysaccharide stimulates protein tyrosine phosphorylation in macrophages.Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.Differentiating agents in malignant disease.
P2860
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P2860
Phenotypic change from transformed to normal induced by benzoquinonoid ansamycins accompanies inactivation of p60src in rat kidney cells infected with Rous sarcoma virus.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Phenotypic change from transfo ...... ected with Rous sarcoma virus.
@en
type
label
Phenotypic change from transfo ...... ected with Rous sarcoma virus.
@en
prefLabel
Phenotypic change from transfo ...... ected with Rous sarcoma virus.
@en
P2093
P2860
P356
P1476
Phenotypic change from transfo ...... ected with Rous sarcoma virus.
@en
P2093
P2860
P304
P356
10.1128/MCB.6.6.2198
P407
P577
1986-06-01T00:00:00Z