Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy. - Wikidata - awgldk - TriplyDB

Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy.

Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy.

http://www.wikidata.org/entity/Q37073804

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Fundamental role of pan-inflammation and oxidative-nitrosative pathways in neuropathogenesis of Alzheimer's disease in focal cerebral ischemic rats Fundamental role of pan-inflammation and oxidative-nitrosative pathways in neuropathogenesis of Alzheimer's disease Tau-targeted treatment strategies in Alzheimer's disease Rescue from tau-induced neuronal dysfunction produces insoluble tau oligomers Animal models for Alzheimer's disease and frontotemporal dementia: a perspective Heat shock protein responses to aging and proteotoxicity in the olfactory bulb.Heat shock proteins in neurodegenerative disorders and aging Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition.Ketogenic diet improves motor performance but not cognition in two mouse models of Alzheimer's pathology Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease Novel marker for the onset of frontotemporal dementia: early increase in activity-dependent neuroprotective protein (ADNP) in the face of Tau mutation.The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.Acetylation: a new key to unlock tau's role in neurodegeneration Hsc70 rapidly engages tau after microtubule destabilization LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis.Molecular chaperone dysfunction in neurodegenerative diseases and effects of curcumin.Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice.Casein kinase II induced polymerization of soluble TDP-43 into filaments is inhibited by heat shock proteins.Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy Molecular chaperones and regulation of tau quality control: strategies for drug discovery in tauopathies.Heat shock protein defenses in the neocortex and allocortex of the telencephalon.Heat shock response and insulin-associated neurodegeneration.In vivo functional brain mapping in a conditional mouse model of human tauopathy (tauP301L) reveals reduced neural activity in memory formation structures Imbalance of Hsp70 family variants fosters tau accumulation.Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model.Dysfunctional nucleus tractus solitarius: its crucial role in promoting neuropathogenetic cascade of Alzheimer's dementia--a novel hypothesis.Potential synergy between tau aggregation inhibitors and tau chaperone modulators.Hsp90 activator Aha1 drives production of pathological tau aggregates.Molecular Mechanisms Underlying Neuroprotective Effect of Intranasal Administration of Human Hsp70 in Mouse Model of Alzheimer's Disease.Dysfunctional Sensory Modalities, Locus Coeruleus, and Basal Forebrain: Early Determinants that Promote Neuropathogenesis of Cognitive and Memory Decline and Alzheimer's Disease.Noncontact Rotational Head Injury Produces Transient Cognitive Deficits but Lasting Neuropathological Changes.An acetylation-phosphorylation switch that regulates tau aggregation propensity and function.Metabolic changes over the course of aging in a mouse model of tau deposition.Targeting Neuroinflammation to Treat Alzheimer's Disease.In Vivo Tau Imaging for a Diagnostic Platform of Tauopathy Using the rTg4510 Mouse Line.In Vivo Visualization of Tau Accumulation, Microglial Activation, and Brain Atrophy in a Mouse Model of Tauopathy rTg4510.

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Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy.

http://www.wikidata.org/entity/Q37073804

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article científic

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bilimsel makale

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scientific article published on 12 December 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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Aging analysis reveals slowed ...... in a mouse model of tauopathy.

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Aging analysis reveals slowed ...... in a mouse model of tauopathy.

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Aging analysis reveals slowed ...... in a mouse model of tauopathy.

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Aging analysis reveals slowed ...... in a mouse model of tauopathy.

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Aging analysis reveals slowed ...... in a mouse model of tauopathy.

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Aging analysis reveals slowed ...... in a mouse model of tauopathy.

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AJPATH.2009.080764

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The American Journal of Pathology

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Aging analysis reveals slowed ...... in a mouse model of tauopathy.

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Amelia Johnson

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Chad Dickey

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Clara Kraft

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Daniel Lee

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David Morgan

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Jada Lewis

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Laura Anderson

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Lester I Binder

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Lori Lebson

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Rohan de Silva

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Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions.

Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse

Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity.

Akt and CHIP coregulate tau degradation through coordinated interactions

CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70

Tau suppression in a neurodegenerative mouse model improves memory function

Tau filament formation in transgenic mice expressing P301L tau.

Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy.

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228-238

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scholarly article

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10.2353/AJPATH.2009.080764

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1

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174

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Dennis W. Dickson

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2008-12-12T00:00:00Z

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19074615

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2631335

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