Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset - Wikidata - awgldk - TriplyDB

Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset

Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset

http://www.wikidata.org/entity/Q37073913

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Observing Huntington's Disease: the European Huntington's Disease Network's REGISTRY Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging Four decades of neurodegenerative disease research: how far we have come!Intrabodies as neuroprotective therapeutics Genetics and neuropathology of Huntington's disease Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striatal neuron morphology and dopamine metabolism High-content chemical and RNAi screens for suppressors of neurotoxicity in a Huntington's disease model NMDA receptor gene variations as modifiers in Huntington disease: a replication study The struggle by Caenorhabditis elegans to maintain proteostasis during aging and disease Environmental enrichment and brain repair: harnessing the therapeutic effects of cognitive stimulation and physical activity to enhance experience-dependent plasticity Sex Differences in Circadian Dysfunction in the BACHD Mouse Model of Huntington's Disease A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease Aggregation of polyQ proteins is increased upon yeast aging and affected by Sir2 and Hsf1: novel quantitative biochemical and microscopic assays Dysregulation of C/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease Before senescence: the evolutionary demography of ontogenesis Unusual structures are present in DNA fragments containing super-long Huntingtin CAG repeats Genomewide association study for onset age in Parkinson disease.Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington's disease motor onset TAA repeat variation in the GRIK2 gene does not influence age at onset in Huntington's disease.CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion.Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region.Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study.Genetic background modulates behavioral impairments in R6/2 mice and suggests a role for dominant genetic modifiers in Huntington’s disease pathogenesis.Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington's disease monkeys.Clinical and genetic data of Huntington disease in Moroccan patients Genetic analysis of the GRIK2 modifier effect in Huntington's disease.Error processing in Huntington's disease.Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease.Normal aging modulates the neurotoxicity of mutant huntingtin.IKKalpha and IKKbeta regulation of DNA damage-induced cleavage of huntingtin.Modeling Huntington disease in yeast: perspectives and future directions.Clinical and genetic features of Huntington disease in Sri Lanka.Copy-number variation of the neuronal glucose transporter gene SLC2A3 and age of onset in Huntington's disease.Developmental Whole Brain White Matter Alterations in Transgenic Huntington's Disease Monkey.Genetic analysis of age at onset variation in spinocerebellar ataxia type 2.Huntington disease models and human neuropathology: similarities and differences CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease.Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors.Prediction of the age at onset in spinocerebellar ataxia type 1, 2, 3 and 6.Investigating the structural impact of the glutamine repeat in huntingtin assembly.

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Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset

http://www.wikidata.org/entity/Q37073913

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on March 2004

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Venezuelan kindreds reveal tha ...... tington's disease age of onset

@en

Venezuelan kindreds reveal tha ...... ington's disease age of onset.

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type

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Venezuelan kindreds reveal tha ...... tington's disease age of onset

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Venezuelan kindreds reveal tha ...... ington's disease age of onset.

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prefLabel

Venezuelan kindreds reveal tha ...... tington's disease age of onset

@en

Venezuelan kindreds reveal tha ...... ington's disease age of onset.

@nl

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PNAS.0308679101

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Proceedings of the National Academy of Sciences of the United States of America

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Venezuelan kindreds reveal tha ...... tington's disease age of onset

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Adam Brickman

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Amarilis Acevedo-Cruz

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Americo Negrette

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Andrew Feigin

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Angela Young

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Anne B Young

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Carol Moskowitz

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Christopher J O'Brien

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David E Housman

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Denise Brocklebank

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P2860

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

Modulation of age at onset in Huntington's disease and spinocerebellar ataxia type 2 patients originated from eastern India

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

Family and molecular data for a fine analysis of age at onset in Huntington disease.

Huntington disease expansion mutations in humans can occur before meiosis is completed.

Huntington's disease: the challenge for cell biologists.

A general test of association for quantitative traits in nuclear families.

A polymorphic DNA marker genetically linked to Huntington's disease.

Trinucleotide repeat length instability and age of onset in Huntington's disease.

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3498-3503

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scholarly article

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10.1073/PNAS.0308679101

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10

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101

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James F. Gusella

Stacey S. Cherny

Bernhard Landwehrmeyer

Jane S. Paulsen

Marcy E. MacDonald

Steven M Hersch

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2004-03-01T00:00:00Z

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5858287

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14993615

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Huntington disease

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373491

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