2'-Deoxy-2'-fluoro-beta-D-arabinonucleosides and oligonucleotides (2'F-ANA): synthesis and physicochemical studies.
about
2'-deoxy-2'-fluoro-beta-D-arabinonucleic acid (2'F-ANA) modified oligonucleotides (ON) effect highly efficient, and persistent, gene silencingThe structural diversity of artificial genetic polymersSmart functional nucleic acid chimeras: enabling tissue specific RNA targeting therapySolution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybridsNMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA-modified aptamerAtomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylaseDifferential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibilityThe solution structure of double helical arabino nucleic acids (ANA and 2'F-ANA): effect of arabinoses in duplex-hairpin interconversionSynthesis and Antisense Properties of Fluoro Cyclohexenyl Nucleic Acid (F-CeNA), a Nuclease Stable Mimic of 2′-Fluoro RNACatalysts from synthetic genetic polymersSynthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicingNanostructures from Synthetic Genetic PolymersSurprising base pairing and structural properties of 2'-trifluoromethylthio-modified ribonucleic acids.Mapping the affinity landscape of Thrombin-binding aptamers on 2΄F-ANA/DNA chimeric G-Quadruplex microarraysImpact of sugar pucker on base pair and mispair stability.Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencingSynthetic genetic polymers capable of heredity and evolution.Semiautomated radiosynthesis and biological evaluation of [18F]FEAU: a novel PET imaging agent for HSV1-tk/sr39tk reporter gene expressionStructural requirements at the catalytic site of the heteroduplex substrate for human RNase H1 catalysis.Properties of arabinonucleic acids (ANA & 20'F-ANA): implications for the design of antisense therapeutics that invoke RNase H cleavage of RNA.Synthesis of DNA oligos containing 2'-deoxy-2'-fluoro-D-arabinofuranosyl-5-carboxylcytosine as hTDG inhibitor.2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase HRational design of novel N-alkyl-N capped biostable RNA nanostructures for efficient long-term inhibition of gene expressionRole of two strictly conserved residues in nucleotide flipping and N-glycosylic bond cleavage by human thymine DNA glycosylase.Chemical modification of siRNA.Unlocked nucleic acid--an RNA modification with broad potential.Antisense drug discovery and development.Probing the Backbone Topology of DNA: Synthesis and Properties of 7',5'-Bicyclo-DNA.Structural Basis for Excision of 5-Formylcytosine by Thymine DNA Glycosylase.G-quadruplex induced stabilization by 2'-deoxy-2'-fluoro-D-arabinonucleic acids (2'F-ANA).2'-fluoro-4'-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity.Synthetic antisense oligodeoxynucleotides to transiently suppress different nucleus- and chloroplast-encoded proteins of higher plant chloroplasts.Synthesis and structural characterization of 2'-fluoro-α-L-RNA-modified oligonucleotides.Antisense inhibition of Flk-1 by oligonucleotides composed of 2'-deoxy-2'-fluoro-beta-D-arabino- and 2'-deoxy-nucleosides.Oligonucleotide therapeutics: chemistry, delivery and clinical progress.Fluorinated Nucleotide Modifications Modulate Allele Selectivity of SNP-Targeting Antisense Oligonucleotides.Synthesis of some 2'-fluoro-2'-deoxy-3'-C-ethynyl and 3'-C-vinyl-beta-D-lyxofuranosyl nucleosides.Antisense 2'-Deoxy, 2'-Fluroarabino Nucleic Acids (2'F-ANAs) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids.Synthesis of protected 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides.Solid-phase synthesis of 2'-deoxy-2'-fluoro- beta-D-oligoarabinonucleotides (2'F-ANA) and their phosphorothioate derivatives.
P2860
Q25255757-CE29A664-73D6-4289-885B-36E56584602CQ26775558-EB5FEB64-A2A0-4E28-B217-E97714996F14Q27025832-10AB347B-ABD9-42D7-BB94-071830B61E55Q27635939-2BB40CDD-FCC6-4471-AF8A-B71C5DC4FCFCQ27647789-65235415-DB3D-40F6-B165-32E031A6CFBAQ27657850-5831817A-A386-435C-B3B9-B98BDC07F7B6Q27658949-9D79984C-9CA5-4FB8-81E2-1C850FE489C4Q27670744-D8E87A1D-1B88-4417-9D13-E02B2F812FE0Q27679106-0A0C723B-2169-4C26-B447-AA13456A4D5AQ28253153-3ED1C41A-1C4C-400F-BB73-22E6C4B87935Q28830393-32FFF57F-3855-44A8-91F1-5B6552AFD227Q28831369-F1E0D7F1-4587-4EDE-B600-F668411FB826Q30808960-8C1296D5-D0E4-4096-B0CC-D1FFFE45A8B3Q33557641-57D74E10-A233-40B7-9323-959DD24D50A8Q33622112-7F3C3148-44A2-41A6-9739-BFACB72C05CAQ34020246-325D359B-F8D0-44DE-A54E-DE7E52599011Q34031569-8D01C95A-520B-4A94-B875-382DF0374332Q34077927-ECAB09A0-6CA6-4D46-BD26-A252A0011906Q34327729-D1DF4C26-638F-4CDF-A520-CE5765F85E6CQ34373545-A67476E8-BDD5-4A28-BC16-EFD3B4D1560AQ36034586-BA0CAD95-0075-4B31-8461-7489CC900901Q36908756-E7CDDB4B-A086-45FB-8638-5E9430E81C77Q36914607-9175563B-0B08-4D85-9168-CB00ADCDDE2EQ37479458-C24EB7B2-D1CD-4F0F-84E3-3B1E7E0B5A68Q37655882-41077638-8B8D-4940-8423-8C2F203CCFDAQ37856768-FF73C95D-97F6-4909-A4F3-884FF08EDCCFQ37859009-26577D4B-8EE8-4909-B842-0D7039E7984DQ38288844-8CF04ED2-5FE3-4720-9258-1AD737FC1A25Q38290315-8AC729F4-C5BE-4A6F-A0F9-D589A22D89C0Q38299950-42D5AF96-EEFF-4892-8758-CD1859ADE0C4Q38305021-F606685B-F33F-4125-82D2-031C5A1B7D2CQ38331315-AF5426E3-95ED-4B1F-A074-6D18FDAD3A84Q38333758-BB56F136-CE78-4F4B-B1DC-6B8431BB106BQ38360548-994674EC-88D4-4217-A003-CE3036E4BBB8Q38618638-409198FB-7D96-4E39-8BE0-C2EA734F3234Q38669913-493578C1-567F-4793-B66B-FC3A001E5398Q40358202-BF11372B-E6D1-4ADA-AD17-ABBF3903E712Q41111748-542A1102-15AC-459D-AE0C-32E296D863B3Q42168738-565F6612-4787-4BBA-9368-408CD3441642Q42168788-32019373-98C0-4996-8C95-31078E4C1D35
P2860
2'-Deoxy-2'-fluoro-beta-D-arabinonucleosides and oligonucleotides (2'F-ANA): synthesis and physicochemical studies.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
2'-Deoxy-2'-fluoro-beta-D-arab ...... s and physicochemical studies.
@en
2'-Deoxy-2'-fluoro-beta-D-arabinonucleosides and oligonucleotides
@nl
type
label
2'-Deoxy-2'-fluoro-beta-D-arab ...... s and physicochemical studies.
@en
2'-Deoxy-2'-fluoro-beta-D-arabinonucleosides and oligonucleotides
@nl
prefLabel
2'-Deoxy-2'-fluoro-beta-D-arab ...... s and physicochemical studies.
@en
2'-Deoxy-2'-fluoro-beta-D-arabinonucleosides and oligonucleotides
@nl
P2860
P356
P1476
2'-Deoxy-2'-fluoro-beta-D-arab ...... s and physicochemical studies.
@en
P2093
P2860
P304
P356
10.1093/NAR/28.18.3625
P407
P577
2000-09-01T00:00:00Z