Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN. - Wikidata - awgldk - TriplyDB

Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN.

Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN.

http://www.wikidata.org/entity/Q39774233

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Voltage-Controlled Enzymes: The New JanusBifrons A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes Molecular mechanisms of peritoneal dissemination in gastric cancer Phosphoinositides: tiny lipids with giant impact on cell regulation MicroRNA Expression Is Altered in an Ovalbumin-Induced Asthma Model and Targeting miR-155 with Antagomirs Reveals Cellular Specificity p53 Down regulates PDGF-induced formation of circular dorsal ruffles in rat aortic smooth muscle cells PTEN is a protein tyrosine phosphatase for IRS1 PTEN regulates cilia through Dishevelled.Upregulation of PTEN in glioma cells by cord blood mesenchymal stem cells inhibits migration via downregulation of the PI3K/Akt pathway.Functional analysis of the protein phosphatase activity of PTEN PTEN redundancy: overexpressing lpten, a homolog of Dictyostelium discoideum ptenA, the ortholog of human PTEN, rescues all behavioral defects of the mutant ptenA-microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion Current concepts on the molecular pathology of non-small cell lung carcinoma.Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities The role of DJ-1 in the pathogenesis of endometriosis.A genomic approach to study down syndrome and cancer inverse comorbidity: untangling the chromosome 21.Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes Involvement of TGFβ-induced phosphorylation of the PTEN C-terminus on TGFβ-induced acquisition of malignant phenotypes in lung cancer cells.Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cells A unified nomenclature and amino acid numbering for human PTEN.The protein phosphatase activity of PTEN is essential for regulating neural stem cell differentiation.Molecular Markers with Predictive and Prognostic Relevance in Lung Cancer Engineering FKBP-Based Destabilizing Domains to Build Sophisticated Protein Regulation Systems.Differential Requirement for Pten Lipid and Protein Phosphatase Activity during Zebrafish Embryonic Development.Phosphatase and tensin homolog is a differential diagnostic marker between nonalcoholic and alcoholic fatty liver disease.Hypoxia-induced modulation of PTEN activity and EMT phenotypes in lung cancers.Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1.The PTEN-Akt pathway impacts the integrity and composition of mitotic centrosomes PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion.Targeting genomic alterations in squamous cell lung cancer.Phosphatidylinositol-3,4,5-trisphosphate: tool of choice for class I PI 3-kinases.The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair.p53 regulation of podosome formation and cellular invasion in vascular smooth muscle cells.PTEN loss in the continuum of common cancers, rare syndromes and mouse models.Genetic alterations of PTEN in human melanoma.Exogenous induction of unphosphorylated PTEN reduces TGFβ-induced extracellular matrix expressions in lung fibroblasts.Controlling PTEN (Phosphatase and Tensin Homolog) Stability: A DOMINANT ROLE FOR LYSINE 66.Direct regulation of transforming growth factor β-induced epithelial-mesenchymal transition by the protein phosphatase activity of unphosphorylated PTEN in lung cancer cells.PTEN regulates IGF-1R-mediated therapy resistance in melanoma.PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity.

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P2860

Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN.

http://www.wikidata.org/entity/Q39774233

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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2009年學術文章

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Suppression of cellular prolif ...... hosphatase activities of PTEN.

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Suppression of cellular prolif ...... hosphatase activities of PTEN.

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Suppression of cellular prolif ...... hosphatase activities of PTEN.

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Suppression of cellular prolif ...... hosphatase activities of PTEN.

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Suppression of cellular prolif ...... hosphatase activities of PTEN.

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P2860

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

Ubiquitination regulates PTEN nuclear import and tumor suppression

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

Allosteric activation of PTEN phosphatase by phosphatidylinositol 4,5-bisphosphate

Interfacial kinetic analysis of the tumour suppressor phosphatase, PTEN: evidence for activation by anionic phospholipids

Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis

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