A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis
about
p53 Modulates the exonuclease activity of Werner syndrome proteinHMGB1 and HMGB2 cell-specifically down-regulate the p53- and p73-dependent sequence-specific transactivation from the human Bax gene promoterHigh mobility group protein-1 (HMG-1) is a unique activator of p53Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinaseThe requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression.Human papillomavirus oncoprotein E6 inactivates the transcriptional coactivator human ADA3MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-MRegulation of p53 function and stability by phosphorylationThe C terminus of p53 family proteins is a cell fate determinantGeneral transcriptional coactivator PC4 activates p53 functionFunctional promoter upstream p53 regulatory sequence of IGFBP3 that is silenced by tumor specific methylationA ribonucleotide reductase gene is a transcriptional target of p53 and p73Role of insulin-like growth factor binding protein-3 in breast cancer cell growthA novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosisA versatile molecular tagging method for targeting proteins to avian reovirus muNS inclusions. Use in protein immobilization and purificationReassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations.Analysis of p53/BAX in primary colorectal carcinoma: low BAX protein expression is a negative prognostic factor in UICC stage III tumors.Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis.Insights into cancer from transgenic mouse models.Use of a yeast assay to detect functional alterations in p53 in prostate cancer: review and future directions.Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrestmdm2: a bridge over the two tumour suppressors, p53 and Rb.Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene.Apoptosis in cancer.Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis.p53 binds and represses the HBV enhancer: an adjacent enhancer element can reverse the transcription effect of p53Excess beta-catenin promotes accumulation of transcriptionally active p53.An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma.p53 mediates apoptotic crisis in primary Abelson virus-transformed pre-B cells.p53-Dependent and p53-independent induction of insulin-like growth factor binding protein-3 by deoxyribonucleic acid damage and hypoxia.Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes.Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.Transcriptional regulation of ULBP1, a human ligand of the NKG2D receptor.Transcriptional repression by p53 involves molecular interactions distinct from those with the TATA box binding proteinDisparate chromatin landscapes and kinetics of inactivation impact differential regulation of p53 target genesSignificance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides.Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73.Hot-spot mutants of p53 core domain evince characteristic local structural changes.Suppression of tumorigenic and metastatic potentials of human melanoma cell lines by mutated (143 Val-Ala) p53.
P2860
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P2860
A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis
@en
type
label
A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis
@en
prefLabel
A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis
@en
P2093
P2860
P356
P1476
A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis
@en
P2093
P2860
P304
P356
10.1128/MCB.16.9.4961
P407
P577
1996-09-01T00:00:00Z