Unusual pungency from extra-virgin olive oil is attributable to restricted spatial expression of the receptor of oleocanthalSensory characterization of the irritant properties of oleocanthal, a natural anti-inflammatory agent in extra virgin olive oilsPhytochemistry: ibuprofen-like activity in extra-virgin olive oilEffect of oleocanthal and its derivatives on inflammatory response induced by lipopolysaccharide in a murine chondrocyte cell lineFurther evidence for the anti-inflammatory activity of oleocanthal: inhibition of MIP-1α and IL-6 in J774 macrophages and in ATDC5 chondrocytesOlive-oil-derived oleocanthal enhances β-amyloid clearance as a potential neuroprotective mechanism against Alzheimer's disease: in vitro and in vivo studiesOleocanthal in olive oil: between myth and realityAlzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal.Synthesis of (+/-)-Oleocanthal via a Tandem Intramolecular Michael Cyclization-HWE Olefination.Olive phenolics as c-Met inhibitors: (-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer modelsOleocanthal, a phenolic derived from virgin olive oil: a review of the beneficial effects on inflammatory diseaseMolecular mechanisms of inflammation. Anti-inflammatory benefits of virgin olive oil and the phenolic compound oleocanthal.(-)-Oleocanthal rapidly and selectively induces cancer cell death via lysosomal membrane permeabilization.Oleocanthal enhances amyloid-β clearance from the brains of TgSwDI mice and in vitro across a human blood-brain barrier modelOlive Oil-derived Oleocanthal as Potent Inhibitor of Mammalian Target of Rapamycin: Biological Evaluation and Molecular Modeling Studies.Antimicrobial, antioxidant and anti-inflammatory phenolic activities in extra virgin olive oil.Actions of Adjunctive Nutritional Antioxidants in Periodontitis and Prevalent Systemic Inflammatory Diseases.The olive oil phenolic (-)-oleocanthal modulates estrogen receptor expression in luminal breast cancer in vitro and in vivo and synergizes with tamoxifen treatment.Oleocanthal Modulates Estradiol-Induced Gene Expression Involving Estrogen Receptor α.Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor.Oleocanthal inhibits proliferation and MIP-1α expression in human multiple myeloma cells.(-)-Oleocanthal as a c-Met inhibitor for the control of metastatic breast and prostate cancers.(-)-Oleocanthal inhibits growth and metastasis by blocking activation of STAT3 in human hepatocellular carcinoma.Preparative isolation of oleocanthal, tyrosol, and hydroxytyrosol from olive oil by HPCCC.Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau.Direct measurement of oleocanthal and oleacein levels in olive oil by quantitative (1)H NMR. Establishment of a new index for the characterization of extra virgin olive oils.Influence of heat on biological activity and concentration of oleocanthal--a natural anti-inflammatory agent in virgin olive oil.New drugs from ancient natural foods. Oleocanthal, the natural occurring spicy compound of olive oil: a brief history.Quantitative analysis of pungent and anti-inflammatory phenolic compounds in olive oil by capillary electrophoresis.Oleocanthal ameliorates amyloid-β oligomers' toxicity on astrocytes and neuronal cells: In vitro studies.(-)-Oleocanthal exerts anti-melanoma activities and inhibits STAT3 signaling pathway.Cytotoxic Activity of Oleocanthal Isolated from Virgin Olive Oil on Human Melanoma Cells.Modulation of tau protein fibrillization by oleocanthal.New insights on the interaction mechanism between tau protein and oleocanthal, an extra-virgin olive-oil bioactive componentSensory properties of virgin olive oil polyphenols: identification of deacetoxy-ligstroside aglycon as a key contributor to pungencySyntheses of (-)-oleocanthal, a natural NSAID found in extra virgin olive oil, the (-)-deacetoxy-oleuropein aglycone, and related analoguesThe concentration of oleocanthal in olive oil wasteOleocanthal exerts antitumor effects on human liver and colon cancer cells through ROS generationQuantitative method for determination of oleocanthal and oleacein in virgin olive oils by liquid chromatography-tandem mass spectrometry
P921
Q24621359-21AB77BA-97F4-4FD6-B5C2-0C188794AB42Q28237718-F634CFF2-F33E-4F1B-A035-B509951CEDFBQ28270086-8B24D34C-552E-489E-A834-F72152FE1525Q28274908-6423D8B7-A22A-4278-BA06-8D5B709B61F2Q28276558-3AB6D955-0611-4088-8C86-A10C919420CBQ28285617-E595C125-F189-414B-A265-7331D495F5F2Q28290255-9C57C314-9C74-47BD-B726-F72E8D979D8EQ33597771-C46B4692-8A6B-47DC-B7E6-31A761FBFDE8Q33635708-0ABE43C9-07DF-403B-B18A-F52E787E5C50Q33645135-CA4F4F33-5606-4B2D-BFBD-885A1075EB78Q34072400-C8B0F48B-75FC-4F55-A044-EBCD441B3B8DQ34627985-4492F6D2-D8E9-40B9-9379-BC3ABE40D924Q36057085-863EB7F1-9E6B-4CC3-B448-29D2CBDBE52BQ36301505-2D041736-13A7-4404-AB2E-93E7FE5F442DQ37312034-F7C38F52-0C7B-48BA-B3C5-3AE6CA51ECC1Q37946006-7A50753F-9C32-42EE-B863-8A3365F15B59Q38447997-A10380E7-54C8-47DC-B933-A20E2E2B25B3Q38699970-88F8BE7B-8DDE-4991-A955-E707D8C7DF17Q38853991-D9763317-2FD4-4FB7-8369-9AFAFD7B9D9BQ39148082-4F9B78CF-DE3E-4F8F-9E89-E504FC2B2CF1Q39177104-1A803331-3C10-4032-844B-E7AE03651030Q39590655-5CCC1754-E291-4083-9DE8-5259913D2C61Q39711667-AD5A3D6B-DFA1-4EF6-A135-2DE07AD75CE7Q40228201-362B4364-3FAE-4A52-8A54-67BED4B4B28BQ42202910-AADF6B77-27B8-4AEB-830A-C02B37A06BA8Q45964517-0A4503E9-4043-4D18-BDF3-1138CB21EA5AQ46149884-B640E6DB-6C03-4939-A774-436855A9D2BBQ47583487-389AF858-7BF1-4488-B2F7-BED365A78B0EQ47980956-A230E27A-CD11-490C-AFF6-8843DB31BCAAQ51065764-B5DCC00F-69E3-48BD-9308-FE44BB914C48Q51309045-E872875D-D9F6-4A0E-8196-E9F32C231F1AQ51718381-D299DC27-0399-469D-A3AA-11F002982B06Q53332977-4C2C14AF-4F08-4095-B557-04E145F87000Q56774474-2333F86F-3B7A-4931-9535-D1EFC5B3FF4AQ73010938-C32737C2-5A80-4AE4-A66E-EE19E112616DQ80764767-60D7B5BE-EF5B-4B06-B337-17D32D14039EQ83578385-F0D7A187-9BE6-4C49-A16F-3F6F7CC6CF10Q88403223-B450EE92-D515-4142-9237-229AB32A1041Q88746176-6FF5459B-CDBB-4A62-97DC-E4C0B546E6DC
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
(-)-Oleocanthal
@de
(-)-Oleokantal
@sh
(-)-oleocantal
@es
(-)-oleocantale
@it
(-)-oleocanthal
@nl
(-)-oléocanthal
@fr
(-)-олеокантал
@sr
Oleokantal
@sr-el
oleocanthal
@en
Олеокантал
@sr-ec
type
label
(-)-Oleocanthal
@de
(-)-Oleokantal
@sh
(-)-oleocantal
@es
(-)-oleocantale
@it
(-)-oleocanthal
@nl
(-)-oléocanthal
@fr
(-)-олеокантал
@sr
Oleokantal
@sr-el
oleocanthal
@en
Олеокантал
@sr-ec
altLabel
(-)-oleocanthal
@en
(3S,4E)-4-formyl-3-(2-oxoéthyl)hex-4-ènoate de 2-(4-hydroxyphényl)éthyle
@fr
2-(4-hidroksifenil)etil (3S,4E)-4-formil-3-(2-oksoetil)heks-4-enoat
@sr
C17H20O5
@ja
prefLabel
(-)-Oleocanthal
@de
(-)-Oleokantal
@sh
(-)-oleocantal
@es
(-)-oleocantale
@it
(-)-oleocanthal
@nl
(-)-oléocanthal
@fr
(-)-олеокантал
@sr
Oleokantal
@sr-el
oleocanthal
@en
Олеокантал
@sr-ec
P592
P6366
P646
P661
P662
P683
P117
P2017
C/C=C(/C=O)\[C@@H](CC=O)CC(=O)OCCC1=CC=C(C=C1)O
P2067
304.131074
P231
289030-99-5
P233
CC=C(C=O)C(CC=O)CC(=O)OCCC1=CC=C(C=C1)O
P234
1S/C17H20O5/c1-2-14(12-19)15(7 ...... ,10-11H2,1H3/b14-2-/t15-/m0/s1
P235
VPOVFCBNUOUZGG-VAKDEWRISA-N
P274
P3117
DTXSID40183104
P592
CHEMBL2172394
P6366
2778856923
P646
P652
AC7QO6038O