Structural and functional studies with antibodies to the integrin beta 2 subunit. A model for the I-like domain.
about
Integrins Influence the Size and Dynamics of Signaling Microclusters in a Pyk2-dependent MannerMolecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrinRational design of intercellular adhesion molecule-1 (ICAM-1) variants for antagonizing integrin lymphocyte function-associated antigen-1-dependent adhesionStructural basis of integrin regulation and signalingA small molecule agonist of an integrin, alphaLbeta2.Identification of a LFA-1 region involved in the HIV-1-induced syncytia formation through phage-display technology.The N-terminal region and the mid-region complex of the integrin beta 2 subunit.Amino acid residues in the PSI domain and cysteine-rich repeats of the integrin beta2 subunit that restrain activation of the integrin alpha(X)beta(2).Differential role of ICAM ligands in determination of human memory T cell differentiationThe wild boar (Sus scrofa) lymphocyte function-associated antigen-1 (CD11a/CD18) receptor: cDNA sequencing, structure analysis and comparison with homologuesStructural and mechanical functions of integrins.Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin beta subunits.Mannheimia (Pasteurella) haemolytica leukotoxin binding domain lies within amino acids 1 to 291 of bovine CD18.Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2.An isolated, surface-expressed I domain of the integrin alphaLbeta2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond.Locking in alternate conformations of the integrin alphaLbeta2 I domain with disulfide bonds reveals functional relationships among integrin domains.The C-terminal αI domain linker as a critical structural element in the conformational activation of αI integrinsAggregatibacter actinomycetemcomitans leukotoxin requires beta-sheets 1 and 2 of the human CD11a beta-propeller for cytotoxicity.Isoflurane binds and stabilizes a closed conformation of the leukocyte function-associated antigen-1.Integrin alpha(M)beta(2)-mediated cell migration to fibrinogen and its recognition peptides.Differential effects of volatile anesthetics on leukocyte integrin macrophage-1 antigen.Activation of integrin beta-subunit I-like domains by one-turn C-terminal alpha-helix deletionsIntersubunit signal transmission in integrins by a receptor-like interaction with a pull spring.Relating conformation to function in integrin α5β1.GSL-enriched membrane microdomains in innate immune responses.Identification and characterization of two cation binding sites in the integrin beta 3 subunit.Structural basis of blocking integrin activation and deactivation for anti-inflammationCharacterization of binding properties of ICAM-1 peptides to LFA-1: inhibitors of T-cell adhesion.Characterization of the caprine (Capra hircus) beta-2 integrin CD18-encoding cDNA and identification of mutations potentially responsible for the ruminant-specific virulence of Mannheimia haemolytica.The integrin alpha L beta 2 hybrid domain serves as a link for the propagation of activation signal from its stalk regions to the I-like domain.Novel activating and inactivating mutations in the integrin beta1 subunit A domain.Structural Basis for Simvastatin Competitive Antagonism of Complement Receptor 3.Small molecule inhibitors induce conformational changes in the I domain and the I-like domain of lymphocyte function-associated antigen-1. Molecular insights into integrin inhibition.Probing conformational changes in the I-like domain and the cysteine-rich repeat of human beta 3 integrins following disulfide bond disruption by cysteine mutations: identification of cysteine 598 involved in alphaIIbbeta3 activation.Structure-function of the putative I-domain within the integrin beta 2 subunit.Astroglial integrins in the development and regulation of neurovascular unitsIntegrin receptors on tumor cells facilitate NK cell-mediated antibody-dependent cytotoxicity.Novel automated tracking analysis of particles subjected to shear flow: kindlin-3 role in B cells.Generation of a minimal alpha5beta1 integrin-Fc fragment.Defining the repeating elements in the cysteine-rich region (CRR) of the CD18 integrin beta 2 subunit.
P2860
Q27314180-90207B14-E838-4C66-990C-DDE93DFF62CEQ28210618-96AC1E8A-BA34-4905-B7DC-628AE552F78CQ28914750-8C9F0E36-EE4C-49E3-BDDC-368E7B951AEDQ29617618-F915A3A6-1E36-410A-A21C-7524ECFCD5E9Q30478693-2F23D2BC-2B19-4FE2-B250-D88FC58F7DB3Q30651744-E95C6378-0629-46CE-8791-01DE2EC551FAQ30997990-5C3B0340-0E76-41A1-BAE4-503B91DF3618Q31628426-B333E26D-D237-4BAB-933A-DC2651EDF3BEQ33269626-7F1A5A52-89D3-4E5F-B7BF-DC3EC6B5A882Q33302692-E40C1058-1068-4BA5-A67C-EAB9939F8904Q33639654-5B88B43B-D7FF-4E58-84CA-AC3543A643A2Q33944363-685EBAF1-4EB2-40B5-96CA-15D5BB49AB3CQ34033814-BF92CB1E-E79A-4FAE-8FFC-B05E748EF9F0Q34093237-3EA0CF0C-6FCE-4886-8D67-376B8BB24256Q34461123-DE33D0D6-77FD-42BD-8508-4CA7FC36E5BBQ34461566-953670F3-FFA5-4750-83A8-4C6CB0373ABFQ35605015-11FDBDD7-2E6E-46B6-B786-7969784A4574Q36282882-928DB2EB-4611-4FFF-AB3F-B4270D5A2F38Q36329829-BC5D99F2-50A8-42CE-8342-748F0ADA5E52Q36369005-169AA565-1166-492A-8759-2C647BF73ECBQ36431023-77DC2E72-EF9A-43F0-9F4A-BB32540E839DQ36601714-CB3BBC95-FADA-46D9-B377-555BDC0229CDQ36852850-8396DDD4-4F8E-4D5D-AE80-86726D871397Q37086651-5F8056DE-57B1-4E24-B595-0DDE84E731D6Q38086070-8A353298-932A-4868-A4DB-D39D42AE6653Q38292901-AE5C96C6-CE4E-41C8-8430-A43ECF2E8640Q38543641-E6BB6960-0D32-404F-8701-49FA4323DCA2Q40241335-2154384B-4C46-4FEA-B1E3-C997B9046E3CQ40472074-59D8CBAC-5763-4130-941E-8425B4A5FB8AQ40509381-90E7FC14-BF93-431C-BDD6-82C0F771E3A1Q40589353-95CA2EF0-80A0-4D65-9078-685F3CDB5DAFQ40638258-086FC248-367C-4579-BA13-920886FBCCB4Q40758356-A4736F53-C2FC-49A7-A9B1-F44964D5B658Q40785864-D276A125-CA65-4079-AC3E-B77676C30AA6Q40817171-4E952766-60CD-4FB5-9378-FB1772F9D6B9Q42427133-FE8AD2D8-61A7-45A8-AD55-F089A9AD4A6AQ42544946-9394AB58-1A5D-4215-93F7-23CD02C2DE65Q42584075-A735F0D2-7D8F-45C2-A744-A77C1C37DFDCQ43627902-3902C2EE-1F34-4267-9255-A887D6659937Q43737349-B6294BBA-90A3-43B2-A88E-0AE06C5279EE
P2860
Structural and functional studies with antibodies to the integrin beta 2 subunit. A model for the I-like domain.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Structural and functional stud ...... A model for the I-like domain.
@en
type
label
Structural and functional stud ...... A model for the I-like domain.
@en
prefLabel
Structural and functional stud ...... A model for the I-like domain.
@en
P2093
P356
P1476
Structural and functional stud ...... A model for the I-like domain.
@en
P2093
P304
21514-21524
P356
10.1074/JBC.M002286200
P407
P577
2000-07-01T00:00:00Z